ArticlePathogens and disease2016
Actin-based motility of bacterial pathogens: mechanistic diversity and its impact on virulence.
Article in Pathogens and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- Performance of the pBHR1 mobilization protein MobV and its role in stable plasmid expression inMicrobiology spectrum · 2026Article
- GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis.The EMBO journal · 2026Article
- The NLRP6 inflammasome is activated by sterile or pathogen-induced endolysosomal damage.The EMBO journal · 2026Article
- Pathogen-Mediated Cell Fusion and Actin Cytoskeleton.Advances in experimental medicine and biology · 2026Review
- The host calcium system contributes to intracellularInfection and immunity · 2025Article
- On the generation of force required for actin-based motility.Scientific reports · 2024Article
- Article
- PathogenicJournal of bacteriology · 2024Review
- Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core.Journal of structural biology · 2023Article
- Functional Mimicry of Eukaryotic Actin Assembly by Pathogen Effector Proteins.International journal of molecular sciences · 2022Review
- Monoclonal Antibodies OpsonizeJournal of bacteriology · 2021Article
- Article
- Xanthomonas effector XopR hijacks host actin cytoskeleton via complex coacervation.Nature communications · 2021Article
- The enigmatic biology of rickettsiae: recent advances, open questions and outlook.Pathogens and disease · 2021Review
- The Actin Cytoskeleton Mediates Transmission of "Applied and environmental microbiology · 2021Article
- Transcriptome-Wide Comparisons and Virulence Gene Polymorphisms of Host-Associated Genotypes of the Cnidarian Parasite Ceratonova shasta in Salmonids.Genome biology and evolution · 2020Article
- Article
- Identification of novel targets for host-directed therapeutics against intracellular Staphylococcus aureus.Scientific reports · 2019Article
- Review
- Principles of intracellular bacterial pathogen spread from cell to cell.PLoS pathogens · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A diverse spectrum of intracellular bacterial pathogens that inhabit the cytosol have evolved the ability to polymerize actin on their surface to power intracellular actin-based motility (ABM). These include species of Listeria, Burkholderia and Rickettsia, as well as Shigella and Mycobacteria Here, we provide an overview of the roles of bacterial ABM in survival and virulence. Moreover, we survey the molecular mechanisms of actin polymerization in host cells and describe how bacterial pathogens mimic or harness the full diversity of these mechanisms for ABM. Finally, we present ABM through a new lens by comparing motility mechanisms between related species of Listeria, Burkholderia, and Rickettsia Through these comparisons, we hope to illuminate how exploitation of different actin polymerization mechanisms influences ABM as well as pathogenicity and virulence in humans and other animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.