ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2016
[Relationship between vitamin D deficiency and early-onset neonatal sepsis].
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- A systematic review and meta-analysis of Vitamin D status and clinical outcomes in critically ill neonates.Frontiers in nutrition · 2026Pooled it
- Correlation between serum vitamin D level and acute invasive enteritis in children.Immunity, inflammation and disease · 2024Article
- Association of low vitamin D level and full-term early-onset neonatal sepsis; a case-control study.Italian journal of pediatrics · 2024Article
- Effects of vitamin D on neonatal sepsis: A systematic review and meta-analysis.Food science & nutrition · 2021Article
- Investigation of association between maternal 25-OH vitamin D serum levels and neonatal early onset sepsis in newborns by evaluating key factors.Lipids in health and disease · 2019Article
- Effects of vitamin D on apoptosis of T-lymphocyte subsets in neonatal sepsis.Experimental and therapeutic medicine · 2018Article
- [Relationship between vitamin D deficiency and necrotizing enterocolitis in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of vitamin D level on early-onset sepsis (EOS) in neonates.
methodsSeventy-eight full-term neonates with EOS were used as the research group (EOS group). sixty healthy full-term neonates without clinical and/or laboratory features related to infections were used as the control group. Blood samples of the neonates and their mothers in both groups were collected within 72 hours of delivery to determine 25-hydroxyvitamin D(25-OHD) levels. The rate of vitamin D deficiency in the neonates and the level of 25-OHD supplemented to their mothers during pregnancy were compared between the two groups.
resultsThere was a significant positive correlation between the serum level of 25-OHD of the mothers and that of the neonates in both groups (EOS group: r=0.797, P<0.01; control group: r=0.929, P<0.01). The neonates and their mothers in the EOS group had significantly lower 25-OHD levels than those in the control group (P<0.01). The rate of vitamin D deficiency among the neonates in the EOS group was significantly higher than that of the control group (P<0.01). The level of vitamin D supplemented to the mothers during the last 3 months of pregnancy in the EOS group was significantly lower than that in the control group (P<0.01).
conclusionsLow serum level of 25-OHD is associated with the development of early-onset sepsis in full-term neonates.
Indexed as
Identifiers
27655531PMC7389977W2531505600What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.