Evidence map›Paper›PMID 27655150›Full record

ArticleNanotechnology2016

Functionalized magnetic microparticle-based colorimetric platform for influenza A virus detection.

Chaohui Chen, Zhong Zou, Lu Chen, Xinghu Ji, Zhike He

Open access · greenAbstract read
In one paragraph

Article in Nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection.Angewandte Chemie (International ed. in English) · 2025
    Review
  3. Review
  4. Aptamer-Based Technologies for Parasite Detection.Sensors (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Aptamer-based biosensors for virus protein detection.Trends in analytical chemistry : TRAC · 2022
    Review
  7. Review
  8. Aptamers: A prospective tool for infectious diseases diagnosis.Journal of clinical laboratory analysis · 2022
    Review
  9. Aptamers for Viral Detection and Inhibition.ACS infectious diseases · 2022
    Review
  10. Aptamers-Diagnostic and Therapeutic Solution in SARS-CoV-2.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Review
  13. Aptamers for Anti-Viral Therapeutics and Diagnostics.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Review
  16. Review-Chemical and Biological Sensors for Viral Detection.Journal of the Electrochemical Society · 2020
    Article
  17. Visual Detection ofSensors (Basel, Switzerland) · 2019
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chaohui ChenKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
Zhong ZouKey Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.
Lu ChenKey Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.
Xinghu JiKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
Zhike HeKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
Huazhong Agricultural University · CNWuhan University · CNJianghan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A colorimetric platform for influenza A virus detection was developed by using the high efficiency of enzymatic catalysis and the reduction of gold ions with hydrogen peroxide. Aptamer-functionalized magnetic microparticles were synthesized to capture the influenza A virus. This was followed by the binding of ConA-GOx-AuNPs to the H3N2 virus through the ConA-glycan interaction. The sandwich complex was subsequently dispersed in glucose solution to trigger an enzymatic reaction to produce hydrogen peroxide, which controlled the growth of gold nanoparticles and produced colored solutions. The determination of H3N2 concentration was realized by comparing the two differently colored gold nanoparticles. This method could detect the target virus as low as 11.16 μg ml(-1). Furthermore, it opens new opportunities for sensitive and colorimetric detection of viruses and proteins.

Indexed as

ColorimetryBiosensing TechniquesGoldInfluenza A Virus, H3N2 SubtypeMetal NanoparticlesGold

Identifiers

PMID27655150
PMCPMC7103194
OpenAlexW2522531689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.