Evidence map›Paper›PMID 27655115›Full record

ArticleTrials2016

A home-based exercise intervention for caregivers of persons with dementia: study protocol for a randomised controlled trial.

Wai Chi Chan, Nicola Lautenschlager, Briony Dow, Suk Ling Ma, Corine Sau Man Wong, Linda Chiu Wa Lam

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02132039 (A Randomised Controlled Trial of Home-based Exercise Intervention for Caregivers of Persons With Dementia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02132039 naunknown statusnot on this map

A Randomised Controlled Trial of Home-based Exercise Intervention for Caregivers of Persons With Dementia

TypeinterventionalSponsorThe University of Hong KongRan2014 to 2017Enrolled272ConditionsDepressionArms12-step sitting Tai Chi Chuan, Control
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Wai Chi ChanDepartment of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong. waicchan@hku.hk.ORCID http://orcid.org/0000-0002-7324-0553
Nicola LautenschlagerAcademic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia.
Briony DowNational Ageing Research Institute, The University of Melbourne, Melbourne, VIC, Australia.
Suk Ling MaDepartment of Psychiatry, The Chinese University of Hong Kong, Tai Po Hospital, Tai Po, Hong Kong.
Corine Sau Man WongDepartment of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
Linda Chiu Wa LamDepartment of Psychiatry, The Chinese University of Hong Kong, Tai Po Hospital, Tai Po, Hong Kong.
Chinese University of Hong Kong · HKQueen Mary Hospital · CNThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFamily members, who provide the majority of care for persons with dementia, are especially vulnerable to developing depression. Interventions targeting their depressive symptoms have been proposed but their efficacies vary considerably. It has been suggested that interventions carried out in the home setting and involving both caregivers and care recipients are more efficacious. This study aims to compare the efficacy of a home-based structured exercise programme involving both persons with dementia and their caregivers with nonexercise social contact control in treating depression among caregivers. METHODS/

designThis is a parallel-group, assessor-blind, randomised controlled trial. A total of 136 caregiver-care-recipient dyads (i.e. 272 participants in total) will be recruited and randomly allocated to either a home-based structured exercise (sitting Tai Chi) group or a social contact control group. The trial comprises a 3-month intervention phase followed by an extended observation phase of another 3 months. All participants will be assessed at baseline, 6th week, 12th week and 24th week. The primary outcome will be the reduction in depression among caregivers as measured by the Hamilton Rating Scale for Depression. The secondary outcomes will be burden, quality of life, cognitive performance and balance ability of the caregivers, as well as the neuropsychiatric symptoms, cognitive function, balance and functional abilities of the persons with dementia. We will also examine whether the brain-derived neurotrophic factor gene modulates mood changes in response to exercise. DISCUSSION: The findings offer a potential avenue of intervention by providing a low-cost, safe and effective treatment for depression among dementia caregivers, which may in turn also benefit the care recipients.

trial registrationClinicalTrials.gov Identifier: NCT02132039 , registered on 28 April 2014.

Indexed as

CaregiversDementiaDepressionHome-based exerciseRandomised controlled trialTai Chi

Identifiers

PMID27655115
PMCPMC5031263
OpenAlexW2521344850

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.