Evidence map›Paper›PMID 27654872›Full record

ReviewPharmacogenetics and genomics2016

PharmGKB summary: very important pharmacogene information for MT-RNR1.

Julia M Barbarino, Tracy L McGregor, Russ B Altman, Teri E Klein

Abstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  16. Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia M BarbarinoDepartments of aGenetics bBioengineering, Stanford University, Stanford, California cDepartment of Pediatrics, Division of Medical Genetics and Genomic Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Tracy L McGregor
Russ B Altman
Teri E Klein

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
MTRNR1 Aminoglycoside Ototoxicity Outcomes and Parental Perceptions of TestingK23HD000001 · NICHD · VANDERBILT UNIVERSITY · PI MCGREGOR, TRACY L. · 2012 to 2014
$528k
NICHD NIH HHS K23 HD000001NIGMS NIH HHS R24 GM061374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsAminoglycosidesAnti-Bacterial AgentsDNA, MitochondrialGenetic Predisposition to DiseaseGenetic VariationHearing LossHumansMutationRibonucleotide ReductasesRNA, RibosomalAminoglycosidesAnti-Bacterial AgentsDNA, MitochondrialRibonucleotide ReductasesRNA, RibosomalRNA, ribosomal, 12S

Identifiers

PMID27654872
PMCPMC5083147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.