Evidence map›Paper›PMID 27654689›Full record

ArticleLab animal2016

A comparison of sexing methods in fetal mice.

Scott Deeney, Kyle N Powers, Timothy M Crombleholme

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Lab animal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Scott DeeneyLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado School of Medicine, and Division of Pediatric General, Thoracic and Fetal Surgery, Colorado Children's Hospital, Aurora, Colorado.
Kyle N PowersLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado School of Medicine, and Division of Pediatric General, Thoracic and Fetal Surgery, Colorado Children's Hospital, Aurora, Colorado.
Timothy M CrombleholmeLaboratory for Fetal and Regenerative Biology, Department of Surgery, University of Colorado School of Medicine, and Division of Pediatric General, Thoracic and Fetal Surgery, Colorado Children's Hospital, Aurora, Colorado.
Children's Hospital Colorado · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate mouse sexing is vital when conducting research examining sexual dimorphisms. Late fetal and newborn mouse pups are more immature than many previously described sexing methods allow. This study compares the sexing accuracy of a newly described internal gonad sexing method to a recently described peritoneal pigmentation sexing method in embryonic day 20 C57BL/6J mouse pups, using Sry genotyping to confirm the sex. The internal gonad sexing method was found to be highly accurate, while the peritoneal pigmentation method was slightly less accurate. Therefore, while Sry genotyping remains the gold standard, immediate and less expensive sexing methods can be performed accurately as early as the late fetal period in C57BL/6J mice.

Indexed as

AnimalsEmbryo, MammalianFemaleGenes, sryGenitaliaGenotyping TechniquesMaleMice, Inbred C57BLPigmentationReproducibility of ResultsSex CharacteristicsSex Determination Analysis

Identifiers

PMID27654689
OpenAlexW2522575947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.