Observational studyJournal of perinatology : official journal of the California Perinatal Association2017
The role of post-mortem MRI in the neonatal intensive care unit.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- The Role of Plain Radiography in Assessing Aborted Foetal Musculoskeletal Anomalies in Everyday Practice.Journal of imaging · 2024Article
- Post-mortem perinatal imaging: what is the evidence?The British journal of radiology · 2023Review
- Usefulness of virtual autopsy in diagnosing pathologies in the paediatric population: A systematic review.SAGE open medicine · 2023Review
- The fundamental need for unifying phenotypes in sudden unexpected pediatric deaths.Frontiers in medicine · 2023Article
- The Role and Place of Thanatoradiological Studies in the Pathological Examination of Fetuses and Newborns.Bulletin of experimental biology and medicine · 2022Article
- Inter-center variation in autopsy practices among regional neonatal intensive care units (NICUs).Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- A pragmatic evidence-based approach to post-mortem perinatal imaging.Insights into imaging · 2021Review
- The Value of Autopsy in Neonates in the 21st Century.Neonatology · 2019Article
- Peri-mortem evaluation of infants who die without a diagnosis: focus on advances in genomic technology.Journal of perinatology : official journal of the California Perinatal Association · 2018Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivePost-mortem examination can provide important information about the cause of death and play a significant role in the bereavement process. Autopsies reveal previous unknown medical problems approximately 20 to 30% of the time. A non-invasive magnetic resonance imaging-based post-mortem examination (PM-MRI) may provide an alternative for families who do not consent to an autopsy. STUDY
designThis study was a prospective observational study of recently expired neonates and infants. Subjects underwent a full body MRI scan (brain, chest, abdomen and pelvis) followed by conventional autopsy if the family desired to have one. MRI results were compared with autopsy findings and the ante-mortem clinical diagnosis. A follow-up survey was conducted to investigate family perceptions of the PM-MRI process.
resultsThirty-one infants underwent full PM-MRI. Of 31 infants, 19 (61%) had complete agreement between the clinician's impression and PM-MRI. Twenty-four infants also had conventional autopsy, with 14/24 (58%) infants having PM-MRI results consistent with autopsy findings. PM-MRI was superior at detection of free intraperitoneal/intrathoracic air and hepatic iron overload. Whole-body PM-MRI did not have the resolution to detect focal/microscopic injury, vascular remodeling and some forms of brain injury. Of those families who remembered the PM-MRI findings, the majority felt that the information was useful.
conclusionsPM-MRI studies may provide an important adjunct to conventional autopsy and a substitute when the latter is not possible for personal or religious reasons. Clinicians should be aware of, and communicate with the family, the resolution limits of the whole-body PM-MRI to detect certain types of injury.
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Registered trials
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