Evidence map›Paper›PMID 27654348›Full record

ArticleRNA biology2016

The temporally controlled expression of Drongo, the fruit fly homolog of AGFG1, is achieved in female germline cells via P-bodies and its localization requires functional Rab11.

Irina E Catrina, Livia V Bayer, Giussepe Yanez, John M McLaughlin, Kornelia Malaczek, Ekaterina Bagaeva, Salvatore A E Marras, Diana P Bratu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. RNA (New York, N.Y.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Irina E Catrinaa Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Livia V Bayera Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Giussepe Yaneza Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
John M McLaughlina Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Kornelia Malaczeka Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Ekaterina Bagaevaa Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Salvatore A E Marrasc Department of Microbiology, Biochemistry & Molecular Genetics, Public Health Research Institute, New Jersey Medical School - Rutgers , The State University of New Jersey , Newark , NJ , USA.
Diana P Bratua Biological Sciences Department , Hunter College, City University of New York , New York , NY , USA.
Hunter College · USCity University of New York · USRutgers, The State University of New Jersey · USThe Graduate Center, CUNY · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To achieve proper RNA transport and localization, RNA viruses exploit cellular vesicular trafficking pathways. AGFG1, a host protein essential for HIV-1 and Influenza A replication, has been shown to mediate release of intron-containing viral RNAs from the perinuclear region. It is still unknown what its precise role in this release is, or whether AGFG1 also participates in cytoplasmic transport. We report for the first time the expression patterns during oogenesis for Drongo, the fruit fly homolog of AGFG1. We find that temporally controlled Drongo expression is achieved by translational repression of drongo mRNA within P-bodies. Here we show a first link between the recycling endosome pathway and Drongo, and find that proper Drongo localization at the oocyte's cortex during mid-oogenesis requires functional Rab11.

Indexed as

AnimalsDrosophilaDrosophila ProteinsEndosomesFemaleGene Expression RegulationMicrofilament ProteinsOocytesOogenesisProtein Transportrab11 GTP-Binding Proteinsrab GTP-Binding ProteinsDrongo protein, DrosophilaDrosophila ProteinsMicrofilament Proteinsrab11 GTP-Binding ProteinsRab11 protein, Drosophilarab GTP-Binding ProteinsAGFG1cytoskeletonDrongoDrosophilaHIV-1Influenza ARab11

Identifiers

PMID27654348
PMCPMC5100350
OpenAlexW2518649166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.