Evidence map›Paper›PMID 27654172›Full record

ReviewRNA biology2016

Mobile small RNAs and their role in regulating cytosine methylation of DNA.

Thomas J Hardcastle, Mathew G Lewsey

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. DDM1-Mediated TE Silencing in Plants.Plants (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Thomas J Hardcastlea Department of Plant Sciences , University of Cambridge , Cambridge , UK.
Mathew G Lewseyb Department of Animal, Plant and Soil Science, Center for AgriBioscience, School of Life Science , La Trobe University , Bundoora , Australia.
La Trobe University · AUUniversity of Cambridge · GB

Funding

European Research Council 340642
6 · The paper itself

Abstract

Small (s)RNAs of 21 to 24 nucleotides are associated with RNA silencing and methylation of DNA cytosine residues. All sizes can move from cell-to-cell and long distance in plants, directing RNA silencing in destination cells. Twenty-four nucleotide sRNAs are the predominant long-distance mobile species. Thousands move from shoot to root, where they target methylation of transposable elements both directly and indirectly. We derive several classes of interaction between small RNAs and methylation and use these to explore the mechanisms of methylation and gene expression that associate with mobile sRNA signaling.

Indexed as

DNA MethylationCytosineDNA, PlantDNA Transposable ElementsGene Expression Regulation, PlantPlant RootsPlantsPlant ShootsRNA, PlantRNA, Small UntranslatedCytosineDNA, PlantDNA Transposable ElementsRNA, PlantRNA, Small UntranslatedHistone modificationsplant graftingRNA-directed DNA methylationsmall RNAtranscriptional gene silencing

Identifiers

PMID27654172
PMCPMC5100353
OpenAlexW2508109726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.