Evidence map›Paper›PMID 27653983›Full record

ArticleAmerican journal of physiology. Cell physiology2016

Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis.

Connor J Telles, Sarah E Decker, William W Motley, Alexander W Peters, Ali Poyan Mehr, Raymond A Frizzell, John N Forrest

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Sugar uptake, metabolism, and chloride secretion in the rectal gland of the spiny dogfishAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  4. Article
  5. Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?International journal of molecular sciences · 2018
    Review
  6. P2Y receptor regulation of K2P channels that facilitate KAmerican journal of physiology. Cell physiology · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Connor J TellesNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Sarah E DeckerNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
William W MotleyNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Alexander W PetersNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Ali Poyan MehrNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Raymond A FrizzellDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
John N ForrestNephrology Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut; john.forrest@yale.edu.
Mount Desert Island Biological Laboratory · US

Funding

Understanding the role of thyroid hormone signaling during axolotl limb regenerationP20GM104318 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2013 to 2023
$23.0M
Translational StudiesP30DK072506 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PILEWSKI, JOSEPH MARK · 2005 to 2017
$12.5M
Co-chaperone Actions in CFTR BiogenesisR01DK068196 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOETZMAN, ERIC S · 2004 to 2024
$5.8M
THE EPITHELIA OF THE EYE--EFFECT OF ENVIRONMENTAL AGENTSP30ES003828 · NIEHS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI HENSON, JOHN H · 1987 to 2008
$4.1M
ADENOSINE RECEPTORS AND ION TRANSPORT IN EPITHELIAR01DK034208 · NIDDK · YALE UNIVERSITY · PI FORREST, JOHN N · 1986 to 2003
$1.6M
NIDDK NIH HHS P30 DK072506NIDDK NIH HHS R01 DK034208NIDDK NIH HHS R01 DK068196NIEHS NIH HHS P30 ES003828NIGMS NIH HHS P20 GM104318
6 · The paper itself

Abstract

In the shark rectal gland (SRG), apical chloride secretion through CFTR channels is electrically coupled to a basolateral K

Indexed as

Amino Acid SequenceAnimalsChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDNA, ComplementaryDogfishHumansNerve Tissue ProteinsOocytesPotassium ChannelsPotassium Channels, Tandem Pore DomainSalt GlandSharksXenopus laevisChloridesCystic Fibrosis Transmembrane Conductance RegulatorDNA, ComplementaryNerve Tissue ProteinsPotassium ChannelsPotassium Channels, Tandem Pore Domainpotassium channel subfamily K member 3cystic fibrosis transmembrane conductance regulatorfour transmembrane two poreshark rectal glandtask-1 K+ channel

Identifiers

PMID27653983
PMCPMC5206301
OpenAlexW2557478072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.