Evidence map›Paper›PMID 27653982›Full record

ArticleGynecologic oncology2016

Cancer and treatment-related symptoms are associated with mobility disability in women with ovarian cancer: A cross-sectional study.

Grace Campbell, Teresa Hagan, Stephanie Gilbertson-White, Martin Houze, Heidi Donovan

Open access · greenAbstract read
In one paragraph

Article in Gynecologic oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Mobility Assessment Instruments.Seminars in oncology nursing · 2024
    Review
  3. Predictors of persistence of post-chemotherapy symptoms among survivors of solid tumor cancers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  4. Observational
  5. Predictors of the 6-min walk test in patients with ovarian cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  6. Article
  7. Article
  8. Patient preferences for visualization of longitudinal patient-reported outcomes data.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Grace CampbellUniversity of Pittsburgh School of Nursing, 336 Victoria Building, 3500 Victoria Street, Pittsburgh, PA 15261, United States. Electronic address: gbc3@pitt.edu.
Teresa HaganMassachusetts General Hospital, Harvard Medical School, Yawkey Center, 55 Fruit Street, Boston, MA 02114, United States. Electronic address: thagan@mgh.harvard.edu.
Stephanie Gilbertson-WhiteUniversity of Iowa College of Nursing, 50 Newton Road, 444 College of Nursing Building, Iowa City, IA 52242, United States. Electronic address: stephanie-gilbertson-white@uiowa.edu.
Martin HouzeUniversity of Pittsburgh School of Nursing, 336 Victoria Building, 3500 Victoria Street, Pittsburgh, PA 15261, United States. Electronic address: houzemartin@gmail.com.
Heidi DonovanUniversity of Pittsburgh School of Nursing, 336 Victoria Building, 3500 Victoria Street, Pittsburgh, PA 15261, United States. Electronic address: donovanh@pitt.edu.
University of Pittsburgh · USHarvard University · USUniversity of Iowa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Interdisciplinary Training of Nurse Scientists in Cancer Survivorship ResearchT32NR011972 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENDER, CATHERINE M. · 2010 to 2014
$1.3M
A COMMON-SENSE ANALYSIS OF MULTI-SYMPTOM MANAGEMENTF31NR007556 · NINR · UNIVERSITY OF WISCONSIN MADISON · PI DONOVAN, HEIDI S · 2000 to 2002
$76k
NINR NIH HHS F31 NR007556NINR NIH HHS T32 NR011972
6 · The paper itself

Abstract

objectiveTo examine the prevalence of symptom-related mobility disability and identify specific symptoms and other factors associated with mobility disability among a national sample of ovarian cancer (OC) survivors.

methodsDescriptive, correlational secondary analysis of a National Ovarian Cancer Coalition mailed survey of women with a history of OC (n=713). We used the Symptom Representation Questionnaire (SRQ), the MD Anderson Symptom Inventory (MDASI) Interference Scale, and medical and demographic information to determine prevalence of symptom-related mobility disability. We constructed a multiple linear regression model to determine the relative contributions of specific symptoms and other factors to mobility disability.

resultsA majority of the sample (60.0%) reported symptom-related mobility disability. Independent predictors included: > one comorbidity (β=0.112, p=0.001), active OC (β=0.111, p=0.037), abdominal bloating (β=0.097, p=0.006), fatigue (β=0.314, p<0.001), lack of appetite (β=0.072, p=0.045), numbness/tingling (β=0.134, p<0.001), and pain (β=0.194, p<0.001). The model explained 41.5% of the variance in symptom-related mobility disability (R

conclusionsSymptom-related mobility disability is common among women with OC and is associated with medical comorbidities, abdominal bloating, fatigue, lack of appetite, numbness/tingling, and pain. Longitudinal research should clarify the relationship of these symptoms to mobility disability and determine whether effective symptom management minimizes disability.

Indexed as

Mobility LimitationAdultAnorexiaAntineoplastic AgentsCancer PainCross-Sectional StudiesFatigueFemaleHumansMiddle AgedOvarian NeoplasmsPeripheral Nervous System DiseasesSurveys and QuestionnairesAntineoplastic AgentsDisabilityMobilityOvarian cancerPhysical functionSymptom assessment

Identifiers

PMID27653982
PMCPMC5116395
OpenAlexW2520761241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.