ArticleNature communications2016
Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
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- Discovery of new chromosomal markers through repeatome analysis of Caryophyllaeus laticeps (Caryophyllidea).Parasitology research · 2025Article
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- Identifying potential drug targets in the kinomes of two monogenean species.Helminthologia · 2024Article
- Highly resolved genome assembly and comparative transcriptome profiling reveal genes related to developmental stages of tapewormProceedings. Biological sciences · 2024Article
- Phylogenomic Analysis of 155 Helminth Species Reveals Widespread Absence of Oxygen Metabolic Capacity.Genome biology and evolution · 2023Article
- Exploring Evolutionary Relationships within Neodermata Using Putative Orthologous Groups of Proteins, with Emphasis on Peptidases.Tropical medicine and infectious disease · 2023Article
- Cestodes in the genomic era.Parasitology research · 2022Review
- Expansion of Cyclophyllidea Biodiversity in Rodents of Qinghai-Tibet Plateau and the "Out of Qinghai-Tibet Plateau" Hypothesis of Cyclophyllideans.Frontiers in microbiology · 2022Article
- Label-free quantitative proteomics and immunoblotting identifies immunoreactive and other excretory-secretory (E/S) proteins ofFrontiers in immunology · 2022Article
- Case Report: Molecular Diagnosis Revealing an Intestinal Infection of a Hybridized Tapeworm (Frontiers in gastroenterology (Lausanne, Switzerland) · 2022Article
- The Genomes of Two Strains ofFrontiers in cellular and infection microbiology · 2022Article
- Prevalence of meat-transmitted Taenia and Trichinella parasites in the Far East countries.Parasitology research · 2021Review
- The genome of the thin-necked bladder worm Taenia hydatigena reveals evolutionary strategies for helminth survival.Communications biology · 2021Article
- Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation.Communications biology · 2021Article
- Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure.PLoS neglected tropical diseases · 2021Article
- Genomic Signatures of Coevolution between Nonmodel Mammals and Parasitic Roundworms.Molecular biology and evolution · 2021Article
- Article
- Genetic Evolution and Implications of the Mitochondrial Genomes of Two Newly IdentifiedFrontiers in microbiology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
26 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Taenia saginata, Taenia solium and Taenia asiatica (beef, pork and Asian tapeworms, respectively) are parasitic flatworms of major public health and food safety importance. Among them, T. asiatica is a newly recognized species that split from T. saginata via an intermediate host switch ∼1.14 Myr ago. Here we report the 169- and 168-Mb draft genomes of T. saginata and T. asiatica. Comparative analysis reveals that high rates of gene duplications and functional diversifications might have partially driven the divergence between T. asiatica and T. saginata. We observe accelerated evolutionary rates, adaptive evolutions in homeostasis regulation, tegument maintenance and lipid uptakes, and differential/specialized gene family expansions in T. asiatica that may favour its hepatotropism in the new intermediate host. We also identify potential targets for developing diagnostic or intervention tools against human tapeworms. These data provide new insights into the evolution of Taenia parasites, particularly the recent speciation of T. asiatica.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.