Evidence map›Paper›PMID 27653243›Full record

ArticleBiochemistry2016

Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions.

Crystal M Vander Zanden, Rhianon K Rowe, Amanda J Broad, Adam B Robertson, P Shing Ho

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Design of a halogen bond catalyzed DNA endonuclease.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Crystal M Vander ZandenDepartment of Biochemistry & Molecular Biology, Colorado State University , 1870 Campus Delivery, Fort Collins, Colorado 80523-1870, United States.
Rhianon K RoweDepartment of Biochemistry & Molecular Biology, Colorado State University , 1870 Campus Delivery, Fort Collins, Colorado 80523-1870, United States.
Amanda J BroadDepartment of Biochemistry & Molecular Biology, Colorado State University , 1870 Campus Delivery, Fort Collins, Colorado 80523-1870, United States.
Adam B RobertsonDepartment of Molecular Microbiology, Oslo University Hospital , Sognsvannsveien 20, NO-0027 Oslo, Norway.
P Shing HoDepartment of Biochemistry & Molecular Biology, Colorado State University , 1870 Campus Delivery, Fort Collins, Colorado 80523-1870, United States.
Colorado State University · USOslo University Hospital · NO

Funding

Hydroxymethylcytosine Stabilizes Holliday Junctions and Promotes Recombination via Interaction with Endonuclease GF31GM113580 · NIGMS · COLORADO STATE UNIVERSITY · PI VANDER ZANDEN, CRYSTAL MARIE · 2015 to 2016
$68k
NIGMS NIH HHS F31 GM113580
6 · The paper itself

Abstract

5-Hydroxymethylcytosine (

Indexed as

DNA, CruciformNucleic Acid Conformation5-MethylcytosineCalorimetry, Differential ScanningCrystallography, X-RayQuantum TheoryThermodynamics5-hydroxymethylcytosine5-MethylcytosineDNA, Cruciform

Identifiers

PMID27653243
PMCPMC5258817
OpenAlexW2523687276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.