Evidence map›Paper›PMID 27652381›Full record

ArticleCellular and molecular life sciences : CMLS2017

P2Y

Ramasri Sathanoori, Paulina Bryl-Gorecka, Christa E Müller, Laurie Erb, Gary A Weisman, Björn Olde, David Erlinge

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Advances in nucleotide-based P2Y₁ antagonism: implications for cardiovascular therapeutics.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Review
  3. Role of Caveolae and Caveolin in Vascular Physiology and Pathology.Journal of the American Heart Association · 2026
    Review
  4. Article
  5. Article
  6. Integrating molecular and cellular components of endothelial shear stress mechanotransduction.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Role of the Purinergic P2Y2 Receptor in Pulmonary Hypertension.International journal of environmental research and public health · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Purinergic P2YCellular and molecular life sciences : CMLS · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ramasri SathanooriDepartment of Cardiology, Clinical Sciences, Lund University, Tornavägen 10, BMC-D12, Room D1219b, 221 84, Lund, Sweden. Ramasri.Sathanoori@med.lu.se.
Paulina Bryl-GoreckaDepartment of Cardiology, Clinical Sciences, Lund University, Tornavägen 10, BMC-D12, Room D1219b, 221 84, Lund, Sweden.
Christa E MüllerPharmaCenter, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
Laurie ErbDepartment of Biochemistry, University of Missouri, Columbia, USA.
Gary A WeismanDepartment of Biochemistry, University of Missouri, Columbia, USA.
Björn OldeDepartment of Cardiology, Clinical Sciences, Lund University, Tornavägen 10, BMC-D12, Room D1219b, 221 84, Lund, Sweden.
David ErlingeDepartment of Cardiology, Clinical Sciences, Lund University, Tornavägen 10, BMC-D12, Room D1219b, 221 84, Lund, Sweden.
Lund University · SEUniversity of Missouri · USUniversity of Bonn · DE

Funding

Restoring Salivary Gland Function by Reducing Nucleotide-induced InflammationR01DE023342 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI WEISMAN, GARY ANDREW · 2014 to 2018
$2.9M
NIDCR NIH HHS R01 DE023342
6 · The paper itself

Abstract

Endothelial cells release ATP in response to fluid shear stress, which activates purinergic (P2) receptor-mediated signaling molecules including endothelial nitric oxide (eNOS), a regulator of vascular tone. While P2 receptor-mediated signaling in the vasculature is well studied, the role of P2Y

Indexed as

ActinsEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsIntegrinsMutationNitric Oxide Synthase Type IIIPhosphorylationReceptors, Purinergic P2Y2RNA InterferenceRNA, Small InterferingStress FibersStress, MechanicalWound HealingActinsIntegrinsNitric Oxide Synthase Type IIINOS3 protein, humanReceptors, Purinergic P2Y2RNA, Small InterferingFAKIntegrinsP2Y2 receptorsShear stressWound repair

Identifiers

PMID27652381
PMCPMC5272905
OpenAlexW2521899113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.