ArticleSpringerPlus2016
Downward trend in the prevalence of Helicobacter pylori infections and corresponding frequent upper gastrointestinal diseases profile changes in Southeastern China between 2003 and 2012.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The global prevalence of gastric cancer in Helicobacter pylori-infected individuals: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- Research Progress on the Efficacy and Mechanism of Acupuncture in Treating Chronic Gastritis.Diseases (Basel, Switzerland) · 2025Review
- GastritisMIL: An interpretable deep learning model for the comprehensive histological assessment of chronic gastritis.Patterns (New York, N.Y.) · 2025Article
- Prevalence ofIranian journal of microbiology · 2025Article
- Treatment of Chronic Gastritis with Traditional Chinese Medicine: Pharmacological Activities and Mechanisms.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Helicobacter pylori infection.Nature reviews. Disease primers · 2023Review
- Microbial community structure of different tongue fur types in patients with chronic gastritis.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Clinical features and shared mechanisms of chronic gastritis and osteoporosis.Scientific reports · 2023Article
- Mediating effect of gastrointestinal symptoms on dietary behavior and quality of life in Chinese adults with chronic gastritis-a cross-sectional study.Frontiers in medicine · 2023Article
- Relationship AmongSisli Etfal Hastanesi tip bulteni · 2022Article
- Time trends in the prevalence ofThe Journal of international medical research · 2021Article
- Inverse time trends of peptic ulcer and reflux esophagitis show significant association with reduced prevalence ofAnnals of medicine · 2020Article
- Eosinophilic gastroenteritis as a cause of non-Helicobacter pylori, non-gastrotoxic drug ulcers in children.BMC gastroenterology · 2020Article
- Clinical comparative analysis of various duodenal diseases in different age groups.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Article
- Ethnic/racial differences in gastrointestinal symptoms and diagnosis associated with the risk ofClinical and experimental gastroenterology · 2018Article
- Cancer Incidence and Mortality in Asian Countries: A Trend Analysis.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
This present study aims to determine trends in the prevalence of H. pylori infections in Southeastern China between 2003 and 2012, and investigate corresponding changes in the prevalence of upper gastrointestinal diseases. This retrospective study screened 196,442 patients with a mean age of 47.49 ± 14.47 years (age range 5-100 years) in Southeastern China, and a total of 134,812 cases of an endoscopy-referral patient population with digestive symptoms between 2003 and 2012 were enrolled. Based on esophago-gastro-duodenoscopy and pathology, patients diagnosed with chronic gastritis, peptic ulcer, gastric cancer or reflux esophagitis were included in this study. Basic demographic and clinical characteristics such as H. pylori infection status and endoscopic findings were collected and analyzed. Among the 134,812 subjects, mean prevalence of H. pylori infection was 31.97 %; which demonstrated a linear downward trend from 42.40 to 23.82 % (P < 0.001) at an annual rate of 2 % from 2003 to 2012. Similarly, the prevalence of duodenal and gastric ulcer rapidly decreased from 12.65 to 6.57 % and from 7.51 to 3.78 %, respectively; while the prevalence of gastric cancer (from 3.76 to 2.34 %) did not significantly change in the same time period. In contrast, the prevalence of reflux esophagitis increased from 6.19 to 12.80 %. The progressively decreasing prevalence of H. pylori infections from 2003 to 2012 in Southeastern China appears to be linked with the decline of related upper gastrointestinal diseases and increase of some gastrointestinal motility diseases.
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