ArticleThe open microbiology journal2016
A Systemic Review on Staphylococcal Scalded Skin Syndrome (SSSS): A Rare and Critical Disease of Neonates.
Article in The open microbiology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 85 citations in OpenAlex.
- Host genetic variation in desmoglein-1 is associated with susceptibility to staphylococcal scalded skin syndrome.European journal of pediatrics · 2026Article
- Staphylococcal Scalded Skin Syndrome (SSSS) in a Preterm Infant: Clinical Presentation and Role of Next-Generation Sequencing in Toxin Gene Identification-A Case Report.Antibiotics (Basel, Switzerland) · 2025Article
- Staphylococcical scalded skin syndrome: a case series description of a rare and critical disease in a tertiary pediatric center.Italian journal of pediatrics · 2025Article
- Liver Injury in Immune Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Five New Classification Types.Journal of clinical and translational hepatology · 2025Review
- Multidrug-ResistantInfection and drug resistance · 2025Article
- Medicinal plants: bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits - a comprehensive review.Frontiers in immunology · 2025Review
- The Clinical Characteristics and Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2024Article
- Prevalence of Culturable Bacteria and Yeasts in the Nasopharynx Microbiota during the Physiological Course of Pregnancy.Journal of clinical medicine · 2023Article
- Associated Outcomes of Different Intravenous Antibiotics Combined with 2% Mupirocin Ointment in the Treatment of Pediatric Patients with Staphylococcal Scalded Skin Syndrome.Clinical, cosmetic and investigational dermatology · 2023Article
- Staphylococcal Scalded Skin Syndrome and Bullous Impetigo.Medicina (Kaunas, Lithuania) · 2021Review
- The Role of microRNA in Pancreatic Cancer.Biomedicines · 2021Review
- Review
- Antibiotic-resistant profile and the factors affecting the intravenous antibiotic treatment course of generalized Staphylococcal Scalded Skin Syndrome: a retrospective study.Italian journal of pediatrics · 2021Article
- Antimicrobial Resistance and Molecular Analysis ofJournal of Korean medical science · 2021Article
- Management of Infectious Emergencies for the Inpatient Dermatologist.Current dermatology reports · 2021Review
- Bullous impetigo masquerading as pemphigus foliaceus in an adult patient.JAAD case reports · 2020Article
- Impact of Bacterial Toxins in the Lungs.Toxins · 2020Review
- Staphylococcal-scalded skin syndrome: evaluation, diagnosis, and management.World journal of pediatrics : WJP · 2018Review
- Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The symptoms of Staphylococcal scalded skin syndrome (SSSS) include blistering of skin on superficial layers due to the exfoliative toxins released from Staphylococcus aureus. After the acute exfoliation of skin surface, erythematous cellulitis occurs. The SSSS may be confined to few blisters localized to the infection site and spread to severe exfoliation affecting complete body. The specific antibodies to exotoxins and increased clearence of exotoxins decrease the frequency of SSSS in adults. Immediate medication with parenteral anti-staphylococcal antibiotics is mandatory. Mostly, SSSS are resistant to penicillin. Penicillinase resistant synthetic penicillins such as Nafcillin or Oxacillin are prescribed as emergency treatment medicine. If Methicillin-resistant Staphylococcus aureus (MRSA) is suspected), antibiotics with MRSA coverage (e.g., Vancomycin or Linezolid) are indicated. Clindamycin is considered as drug of choice to stop the production of exotoxin from bacteria ribosome. The use of Ringer solution to to balance the fluid loss, followed by maintainence therapy with an objective to maintain the fluid loss from exfoliation of skin, application of Cotrimoxazole on topical surface are greatlly considered to treat the SSSS. The drugs that reduce renal function are avoided. Through this article, an attempt has been made to focus the source, etiology, mechanism, outbreaks, mechanism, clinical manisfestation, treatment and other detail of SSSS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.