Evidence map›Paper›PMID 27651574›Full record

ArticleJournal of obstetrics and gynaecology of India2016

A Retrospective Case-Control Study Evaluating the Role of Mifepristone for Induction of Labor in Women with Previous Cesarean Section.

Chanderdeep Sharma, Anjali Soni, Pawan K Soni, Suresh Verma, Ashok Verma, Amit Gupta

Open access · bronzeAbstract read
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chanderdeep SharmaDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Anjali SoniDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Pawan K SoniDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Suresh VermaDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Ashok VermaDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Amit GuptaDepartment of OBG, Dr. Rajendra Prasad Government Medical College (Dr RPGMC) Kangra at Tanda (HP), Set No. 112, Vivekanand Hostel, Dr RPGMC, Kangra, HP 176001 India.
Government Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of "mifepristone" for induction of labor (IOL) in pregnant women with prior cesarean section (CS).

methodsIn this retrospective study, all pregnant women with prior CS who received oral mifepristone (400 mg) for IOL (as per clear obstetric indications) [group 1] were compared with pregnant women with prior CS who had spontaneous onset of labor (SOL) [group 2], with respect to incidence of vaginal delivery, CS, duration of labor, and various maternal and fetal outcomes.

resultsDuring the study period, 72 women received mifepristone (group 1) for IOL and 346 had SOL (group 2). In group 1 after mifepristone administration, 40 (55.6 %) women had labor onset, and 24 (33.3 %) women had cervical ripening (Bishop Score ≥ 8) within 48 h. There were no statistically significant differences with respect to duration of labor (p value: 0.681), mode of delivery (i.e., normal delivery or CS-p value: 0.076 or 0.120, respectively), or maternal (blood loss or scar dehiscence/rupture uterus), or fetal outcomes (NICU admission) compared to women with previous CS with SOL (group 2). However, the need of oxytocin (p value 0.020) and dose of oxytocin requirement (p value 0.008) were more statistically significant in group 1.

conclusionMifepristone may be considered as an agent for IOL in women with prior CS.

Indexed as

Induction of laborMifepristonePregnancyPrior cesarean delivery

Identifiers

PMID27651574
PMCPMC5016401
OpenAlexW1205110837

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.