ArticlePain medicine (Malden, Mass.)2017
Opioid Overdose History, Risk Behaviors, and Knowledge in Patients Taking Prescribed Opioids for Chronic Pain.
Article in Pain medicine (Malden, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Healthcare Practitioner and Other Professionals' Perspectives on Gabapentinoid Misuse and Dependence: A Systematic Review of Qualitative Studies.European journal of pain (London, England) · 2025Pooled it
- Reliable variability in subjective responses to parenteral hydromorphone administration: empirical confirmation of an opioid non-responder phenotype.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Awareness of the potential consequences of alcohol consumption in the context of chronic pain and prescription opioid use.The American journal of drug and alcohol abuse · 2024Article
- Patient and pharmacist perspectives on opioid misuse screening and brief interventions in community pharmacies.Addiction science & clinical practice · 2024Article
- Screening Incarcerated Women for Opioid Use Disorder.Journal of drug issues · 2024Article
- Identifying and Treating Incarcerated Women Experiencing Substance Use Disorders: A Review.Substance abuse and rehabilitation · 2023Review
- Clinical correlates of drug-related dreams in opioid use disorder.The American journal on addictions · 2022Article
- Hypoxia driven opioid targeted automated device for overdose rescue.Scientific reports · 2021Article
- Using electronic health record's data to assess daily dose of opioids prescribed for outpatients with chronic non-cancer pain.Family medicine and community health · 2021Article
- Longitudinal K-means approaches to clustering and analyzing EHR opioid use trajectories for clinical subtypes.Journal of biomedical informatics · 2021Review
- Impact of policy changes on the provision of naloxone by pharmacies in Ontario, Canada: a population-based time-series analysis.Addiction (Abingdon, England) · 2021Article
- Randomized comparison of two web-based interventions on immediate and 30-day opioid overdose knowledge in three unique risk groups.Preventive medicine · 2019Article
- Opioid Overdose Education for Individuals Prescribed Opioids for Pain Management: Randomized Comparison of Two Computer-Based Interventions.Frontiers in psychiatry · 2018Article
- Opportunities for Emergency Medical Services Intervention to Prevent Opioid Overdose Mortality.Prehospital emergency careArticle
Corrections and comments
- Commented on by
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveMore than 100 million adults in the United States experience chronic pain, and prescription opioids are the third most widely prescribed class of medications. Current opioid overdose prevention efforts almost exclusively target illicit opioid users, and little is known about the experience of overdose among patients being treated for chronic pain (CP) with a prescription opioid.
methodsPatients experiencing CP for three or more months and receiving a prescription opioid for pain management (N = 502) completed a self-report survey that asked questions about opioid overdose history, past 30-day risk factors, and knowledge of opioid overdose, overdose risk, and naloxone.
resultsApproximately one in five CP participants reported experiencing a lifetime overdose. CP participants reported engaging in several behaviors associated with overdose risk and were unlikely to have been trained to administer naloxone. Fewer than 50% of participants answered any knowledge item correctly. The likelihood of having experienced an overdose increased as the scores on the SOAPP-R and DSM-5 opioid use disorder checklist increased, and a SOAPP-R score of 7 or higher or meeting DSM-5 mild opioid use disorder criteria were significantly associated with reporting a lifetime overdose (85% and 84% of participants who experienced an overdose, respectively).
conclusionsOpioid overdose occurs at a high rate among CP participants, and this group is relatively uninformed about risk factors for overdose. Established SOAPP-R and DSM thresholds provide an opportunity to identify participants at elevated risk for having experienced an opioid overdose. These data support development of additional concentrated efforts to prevent overdose among chronic pain patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.