Evidence map›Paper›PMID 27651162›Full record

ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016

Natural products against cancer angiogenesis.

El Bairi Khalid, El-Meghawry El-Kenawy Ayman, Heshu Rahman, Guaadaoui Abdelkarim, Agnieszka Najda

Abstract readReview
PubMed Publisher
In one paragraph

Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Review
  3. Rational Drug Discovery for Isoxazole Based VEGFR2 Inhibition.Current drug discovery technologies · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. The Effects of Abscisic Acid on Angiogenesis in Both ex vivo and in vivo Assays.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
  12. Article
  13. Article
  14. Isookanin Inhibits PGEInternational journal of molecular sciences · 2021
    Article
  15. Article
  16. Review
  17. High-ThroughputFrontiers in oncology · 2021
    Article
  18. Article
  19. Article
  20. The role of microenvironment in tumor angiogenesis.Journal of experimental & clinical cancer research : CR · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

El Bairi KhalidIndependent Research Team in Cancer Biology and Bioactive Compounds, Faculty of Medicine and Pharmacy, University Mohammed 1st, Oujda, Morocco. k.elbairi@ump.ac.ma.
El-Meghawry El-Kenawy AymanDepartment of Molecular Biology GEBRI, University of Sadat City, Sadat, Egypt.
Heshu RahmanDepartment of Veterinary Clinical Diagnosis, Faculty of Veterinary Medicine, University Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Guaadaoui AbdelkarimLaboratory of Genetics and Biotechnology (LGB), Faculty of Sciences, Mohammed 1st University (UMP), Oujda, Morocco.
Agnieszka NajdaQuality Laboratory of Vegetable and Medicinal Materials, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, Leszczyńskiego Street 58, 20-068, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of angiogenesis is quite well-known nowadays. Some medicines and extracts affecting this process are already used routinely in supporting the conventional treatment of many diseases that are considered angiogenic such as cancer. However, we must be aware that the area of currently used drugs of this type is much narrower than the theoretical possibilities existing in therapeutic angiogenesis. Plant substances are a large and diverse group of compounds that are found naturally in fruits, vegetables, spices, and medicinal plants. They also have different anticancer properties. The aim of this literature review article is to present the current state of knowledge concerning the molecular targets of tumor angiogenesis and the active substances (polyphenols, alkaloids, phytohormones, carbohydrates, and terpenes) derived from natural sources, whose activity against cancer angiogenesis has been confirmed.

Indexed as

Biological ProductsChemopreventionEndothelial CellsHumansNeoplasmsNeovascularization, PathologicPlant PreparationsPlants, MedicinalBiological ProductsPlant PreparationsAngiogenesisCancerChemopreventionNatural productsTargets

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.