Evidence map›Paper›PMID 27651143›Full record

ArticleEuropean radiology2017

MR signal in the sacroiliac joint space in spondyloarthritis: a new sign.

Frederiek Laloo, N Herregods, G Varkas, J L Jaremko, X Baraliakos, D Elewaut, F Van den Bosch, K Verstraete, L Jans

Abstract read
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In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. New Bone Formation in Axial Spondyloarthritis: A Review.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Imaging of sacroiliitis: Current status, limitations and pitfalls.Quantitative imaging in medicine and surgery · 2019
    Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Frederiek LalooDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium. Frederiek.Laloo@UGent.be.
N HerregodsDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
G VarkasDepartment of Rheumatology, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
J L JaremkoDepartment of Radiology & Diagnostic Imaging, University of Alberta Hospital, 8440-112 Street, Edmonton, T6G 2B7, Alberta, Canada.
X BaraliakosRheumazentrum Ruhrgebiet, Ruhr-University Bochum, Claudiusstr. 45, D-44649, Herne, Germany.
D ElewautDepartment of Rheumatology, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
F Van den BoschDepartment of Rheumatology, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
K VerstraeteDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
L JansDepartment of Radiology and Medical Imaging, Ghent University Hospital, De Pintelaan 185, B-9000, Gent, Belgium.
Ghent University Hospital · BERuhr University Bochum · DEUniversity of Alberta Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the diagnostic value of MR signal within the sacroiliac (SI) joint space in spondyloarthritis (SpA).

methodsA retrospective analysis of MRIs of SI joints was performed in 363 patients, aged 16-45 years, clinically suspected of sacroiliitis. Intra-articular SI joint MR signals were categorized as normal, high T1 signal, fluid signal, ankylosis or vacuum phenomenon (VP). These MRI findings were correlated with the final diagnosis, according to the ASAS criteria. Sensitivity, specificity, and positive and negative likelihood ratios (LR) and predictive values were calculated.

resultsPresence of intra-articular high T1 signal, fluid signal and ankylosis had a specificity of 95.8 %, 95.3 % and 99.5 % for SpA. High T1 signal, fluid signal and ankylosis were present in 38.4 %, 19.2 % and 17.9 % of SpA patients and in 4.2 %, 4.7 % and 0.5 % of patients without SpA, resulting in LR+ of 9.0, 4.1 and 37.9, respectively. VP was present in 13.2 % of SpA patients and in 20.8 % of patients without SpA, resulting in an LR+ of 0.6.

conclusionsPresence of high T1 signal, fluid signal and ankylosis within the SI joint on MRI have high specificity for SpA. High T1 signal is the most sensitive MRI feature within the SI joint for SpA. KEY POINTS: • MRI of the SI joints is typically obtained for diagnosis of spondyloarthritis. • The MR signal within the SI joint itself reflects features of spondyloarthritis. • Intra-articular high T1 signal, fluid signal and ankylosis are seen in spondyloarthritis. • The vacuum phenomenon makes spondyloarthritis less likely.

Indexed as

AdolescentAdultAnkylosisFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesSacroiliac JointSacroiliitisSensitivity and SpecificitySpondylarthritisYoung AdultAnkylosisMRISacroiliac jointSacroiliitisSpondyloarthritis

Identifiers

PMID27651143
OpenAlexW2523666037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.