Evidence map›Paper›PMID 27650954›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2016

Effects of Lorcaserin on Cocaine and Methamphetamine Self-Administration and Reinstatement of Responding Previously Maintained by Cocaine in Rhesus Monkeys.

Lisa R Gerak, Gregory T Collins, Charles P France

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. The 5-HTPharmacology research & perspectives · 2021
    Trial
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  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Discovery of Highly Potent Serotonin 5-HTACS medicinal chemistry letters · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. OREX-1019: A Novel Treatment of Opioid Use Disorder and Relapse Prevention.The Journal of pharmacology and experimental therapeutics · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa R GerakDepartments of Pharmacology (L.R.G., G.T.C., C.P.F.) and Psychiatry (C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas; and South Texas Veterans Health Care System (G.T.C.), San Antonio, Texas.
Gregory T CollinsDepartments of Pharmacology (L.R.G., G.T.C., C.P.F.) and Psychiatry (C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas; and South Texas Veterans Health Care System (G.T.C.), San Antonio, Texas.
Charles P FranceDepartments of Pharmacology (L.R.G., G.T.C., C.P.F.) and Psychiatry (C.P.F.), University of Texas Health Science Center at San Antonio, San Antonio, Texas; and South Texas Veterans Health Care System (G.T.C.), San Antonio, Texas france@uthscsa.edu.
South Texas Veterans Health Care System · USThe University of Texas Health Science Center at San Antonio · US

Funding

Behavioral Pharmacology of Drug DependenceK05DA017918 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2005 to 2014
$1.2M
Evaluation of the 5-HT2C agonist lorcaserin as potential treatment for cocaine abU01DA034992 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 2013 to 2015
$722k
NIDA NIH HHS K05 DA017918NIDA NIH HHS U01 DA034992
6 · The paper itself

Abstract

Stimulant abuse is a serious public health issue for which there is no effective pharmacotherapy. The serotonin

Indexed as

CocaineMethamphetamineAnimalsBenzazepinesDrug-Seeking BehaviorFemaleMacaca mulattaMaleRecurrenceSelf AdministrationBenzazepinesCocainelorcaserinMethamphetamine

Identifiers

PMID27650954
PMCPMC5118643
OpenAlexW2522422945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.