ArticleJournal of plant research2016
Expression of a putative dioxygenase gene adjacent to an insertion mutation is involved in the short internodes of columnar apples (Malus × domestica).
Article in Journal of plant research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 48 citations in OpenAlex.
- Functional characterization of Acyl-CoA Synthase 1 in tomato branch angle development.BMC plant biology · 2026Article
- LAYLA: development of a comprehensive and cross-sample program for detecting structural variants and its application to citrus cultivars.Breeding science · 2025Article
- Alternative splicing and deletion in S-RNase confer stylar-part self-compatibility in the apple cultivar 'Vered'.Plant molecular biology · 2024Article
- Comparative transcriptome analysis of persimmon somatic mutants (Frontiers in plant science · 2024Article
- Rapid and easy construction of a simplified amplicon sequencing (simplified AmpSeq) library for marker-assisted selection.Scientific reports · 2023Article
- Somatic Mutations in Fruit Trees: Causes, Detection Methods, and Molecular Mechanisms.Plants (Basel, Switzerland) · 2023Review
- Advancing tree genomics to future proof next generation orchard production.Frontiers in plant science · 2023Review
- The Characterization of Columnar Apple GeneInternational journal of molecular sciences · 2022Article
- Stable and efficient transformation of apple.Plant biotechnology (Tokyo, Japan) · 2020Article
- Mikan Genome Database (MiGD): integrated database of genome annotation, genomic diversity, and CAPS marker information for mandarin molecular breeding.Breeding science · 2020Article
- Exploring DNA Variant Segregation Types Enables Mapping Loci for Recessive Phenotypic Suppression of Columnar Growth in Apple.Frontiers in plant science · 2020Article
- Apple whole genome sequences: recent advances and new prospects.Horticulture research · 2019Review
- Loss of a highly conserved sterile alpha motif domain gene (Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Alteration ofHorticulture research · 2018Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Determining the molecular mechanism of fruit tree architecture is important for tree management and fruit production. An apple mutant 'McIntosh Wijcik', which was discovered as a bud mutation from 'McIntosh', exhibits a columnar growth phenotype that is controlled by a single dominant gene, Co. In this study, the mutation and the Co gene were analyzed. Fine mapping narrowed the Co region to a 101 kb region. Sequence analysis of the Co region and the original wild-type co region identified an insertion mutation of an 8202 bp long terminal repeat (LTR) retroposon in the Co region. Segregation analysis using a DNA marker based on the insertion polymorphism showed that the LTR retroposon was closely associated with the columnar growth phenotype. RNA-seq and RT-PCR analysis identified a promising Co candidate gene (91071-gene) within the Co region that is specifically expressed in 'McIntosh Wijcik' but not in 'McIntosh'. The 91071-gene was located approximately 16 kb downstream of the insertion mutation and is predicted to encode a 2-oxoglutarate-dependent dioxygenase involved in an unknown reaction. Overexpression of the 91071-gene in transgenic tobaccos and apples resulted in phenotypes with short internodes, like columnar apples. These data suggested that the 8202 bp retroposon insertion in 'McIntosh Wijcik' is associated with the short internodes of the columnar growth phenotype via upregulated expression of the adjacent 91071-gene. Furthermore, the DNA marker based on the insertion polymorphism could be useful for the marker-assisted selection of columnar apples.
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