ArticleLung2016
Changes in Red Cell Distribution Width During Hospitalization for Community-Acquired Pneumonia: Clinical Characteristics and Prognostic Significance.
Article in Lung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- HRR as a predictor of lung health: insights from the NHANES database.Frontiers in medicine · 2025Article
- Predictive role of red blood cell distribution width and hemoglobin-to-red blood cell distribution width ratio for mortality in patients with COPD: evidence from NHANES 1999-2018.BMC pulmonary medicine · 2024Article
- Relationship between initial red cell distribution width and ΔRDW and mortality in cardiac arrest patients.ESC heart failure · 2024Article
- Article
- Exploring red cell distribution width as a biomarker for treatment efficacy in home mechanical ventilation.BMC pulmonary medicine · 2022Observational
- Red Cell Distribution Width Upon Hospital Admission Predicts Short-Term Mortality in Hospitalized Patients With COVID-19: A Single-Center Experience.Frontiers in medicine · 2021Article
- Back to the Future: Building Up the Case for Exploring Red Blood Cell Morphology in Pulmonary Arterial Hypertension.Annals of the American Thoracic Society · 2019Article
- Can Red Blood Cell Distribution Width be a Potential Marker in the Decision to Perform Tonsillectomy?The Eurasian journal of medicine · 2018Article
- Observational
- Association between post-transplant red cell distribution width and prognosis of kidney transplant recipients.Scientific reports · 2017Article
- Prognostic factors in hospitalized community-acquired pneumonia: a retrospective study of a prospective observational cohort.BMC pulmonary medicine · 2017Observational
- Article
- Hypercapnia is associated with an increased risk of ICU admission and reduced inflammatory responses in AECOPD patients with severe pneumonia.Therapeutic advances in respiratory diseaseObservational
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe investigated outcomes of patients hospitalized with community-acquired pneumonia (CAP) according to the changes in red cell distribution width (RDW).
methodsFor 980 adults, clinical characteristics, outcomes during hospitalization for CAP (transfer to the intensive care unit, treatment with mechanical ventilation, prolonged hospital stay, and death), and all-cause mortality following discharge were compared: according to RDW changes versus stable RDW during hospitalization, and according to normal (≤14.7 %) versus high (>14.7 %) RDW values on admission/discharge.
resultsRDW changes (n = 386) during hospitalization were associated with more severe clinical and laboratory characteristics than stable RDW (n = 594). Changes in RDW strongly predicted poor in-hospital outcomes (p < 0.001). The respective 30, 90-day, and total (median follow-up 54 months) mortality rates were significantly higher (9.8, 16.0 and 43.5 %) among patients with RDW changes, compared to 4.0, 7.6 and 30.5 % among those with stable RDW (p < 0.001 for all comparisons). RDW changes, as well as high RDW (each 1 % increment) on admission and discharge, were powerful predictors of mortality (the respective relative risks 1.41, 1.13, and 1.15, and 95 % confidence intervals 1.13-1.74, 1.08-1.19, and 1.10-1.21).
conclusionsRDW changes during hospitalization for CAP are common and associated with a severe clinical profile. Time-dependent RDW changes strongly predict poor in-hospital outcomes and increased short- and long-term mortality. Repeated RDW determinations during hospitalization for CAP may provide useful prognostic information.
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