SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2017
Treatment for long bone metastases based on a systematic literature review.
Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06918860 (Complications, Implant Survival and Functional Results After Surgical Treatment of Bone Metastases of Proximal Femur With Intramedullary Nail or Prosthetic Reconstruction), which is not on this map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Complications, Implant Survival and Functional Results After Surgical Treatment of Bone Metastases of Proximal Femur With Intramedullary Nail or Prosthetic Reconstruction
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.
- Complication and revision risks of surgical treatment for proximal humerus metastases: a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Pooled it
- Surgical management of tibial metastases: a systematic review.Acta bio-medica : Atenei Parmensis · 2022Pooled it
- Longitudinal survival trends of patients with cancer with surgically managed appendicular metastatic bone disease: systematic review.Canadian journal of surgery. Journal canadien de chirurgiePooled it
- Elective Surgical Care Pathways Are Associated With Lower Fracture Rates at Presentation and Contribute to Superior Clinical Outcomes in Metastatic Bone Disease.Journal of surgical oncology · 2026Article
- Clinical, functional, and quality-of-life outcomes after arthroplasty versus osteosynthesis for metastatic lesions of the proximal femur: a 12-month observational cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Epidemiology and Treatment of Metastatic Lesions Around the Elbow: A Systematic Review.Journal of clinical medicine · 2025Review
- Are we underestimating pathological fracture risk in malignant bone lesions of the proximal humerus?Skeletal radiology · 2025Article
- Differential survival outcomes in upper versus lower extremity metastatic bone disease: a retrospective comparative cohort analysis.Journal of orthopaedic surgery and research · 2025Article
- Periprosthetic Infection after Endoprosthetic Reconstruction for Femoral Bone Metastases: Incidence and Risk Factors, a Single Center Study.Clinics in orthopedic surgery · 2025Article
- Predicting the Risk for Pathological Fracture in Bone Metastases.Current oncology (Toronto, Ont.) · 2025Review
- A comprehensive evaluation of intramedullary devices in the management of femoral metastasis: 30-day outcomes.Proceedings (Baylor University. Medical Center) · 2025Article
- Combination of Elastic Nail(s) and Cementoplasty to Treat Pathological Fractures in Long Bones of the Upper Limb.Cardiovascular and interventional radiology · 2025Article
- Implant survival and risk factors for failure after proximal femoral megaprosthetic reconstruction.SICOT-J · 2025Article
- Palliative care of proximal femur metastatic disease and osteolytic lesions: results following surgical and radiation treatment.BMC cancer · 2024Article
- Use of a newly developed minimally invasive bilateral fixed angle locking system in the treatment of pathological pelvic fractures: a case series.World journal of surgical oncology · 2024Article
- Treatment algorithm for metastatic malignancies in the lower extremities.Molecular and clinical oncology · 2024Article
- Clinical application of LARS tumor tube in joint function reconstruction of tumor type artificial hip replacement.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- A microfluidic organ-on-a-chip: into the next decade of bone tissue engineering applied in dentistry.Future science OA · 2023Review
- Review
- Subtrochanteric fracture in previously treated breast cancer patient handled by proximal femoral nail: A case report.International journal of surgery case reports · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo provide treatment guidelines for patients with long bone metastatic disease based on a systematic review of the literature and to propose an algorithm to guide orthopedic surgeons in decision-making for these patients. MATERIALS AND
methodsWe performed a computerized literature search in MEDLINE, EMBASE and Scopus for studies on patients with long bone metastases. We used the key words "long bones", "metastasis" and "treatment" for published studies that evaluated any treatment for long bone metastases. The articles found were then studied to determine the accuracy of surgical treatments for long bone metastases in every anatomic location, regardless of cancer type, stage and grade of the oncologic disease. Guidelines inferred from this literature review were collected, and an algorithm was proposed.
resultsThere was no clear evidence to support excision of a long bone metastatic lesion at the same surgical setting with internal fixation or prosthetic reconstruction. However, en bloc resection of an isolated bone metastasis may have a beneficial effect on survival. The life expectancy of the patients should be considered for any surgical treatment. Internal fixation preferably with reconstruction nails is indicated for meta-diaphyseal lesions; their rate of mechanical failure and complications ranges from 2 to 22 %. Prosthetic reconstruction is indicated for extensive lytic lesions or pathologic fractures in a meta-epiphyseal locations; their rate of mechanical failure and complications ranges from 3.7 to 35 %. Most of the internal fixation-related complications occur more than 1 year after treatment, in contrast to prosthetic reconstruction-related complications that may occur earlier.
conclusionsIntramedullary nail fixation or prosthetic reconstruction should be chosen on the basis of the location of the lesion, the extent of bone destruction and the stability of the construct to outlast the expected life of the patient. Implant-related complication is similar but may occur earlier with prosthetic reconstructions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.