Evidence map›Paper›PMID 27650362›Full record

Trial reportBritish journal of haematology2018

A phase II study of vascular endothelial growth factor trap (Aflibercept, NSC 724770) in patients with myelodysplastic syndrome: a California Cancer Consortium Study.

Mark H Kirschbaum, Paul Frankel, Timothy W Synold, Jasmine Zain, David Claxton, Joseph Tuscano, Edward M Newman, David R Gandara, Primo N Lara

Open access · bronzeAbstract readClinical Trial, Phase IILetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of haematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Evaluation ofOncology letters · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Mark H KirschbaumDepartment of Hematology/HCT, City of Hope National Medical Center, Duarte, CA, USA.
Paul FrankelDivision of Biostatistics, City of Hope National Medical Center, Duarte, CA, USA.
Timothy W SynoldDepartment of Cancer Biology, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Jasmine ZainDepartment of Hematology/HCT, City of Hope National Medical Center, Duarte, CA, USA.
David ClaxtonDepartment of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Joseph TuscanoDepartment of Internal Medicine, UC Davis Comprehensive Cancer Center, Davis, CA, USA.
Edward M NewmanDepartment of Cancer Biology, Beckman Research Institute of City of Hope, Duarte, CA, USA.
David R GandaraDepartment of Internal Medicine, UC Davis Comprehensive Cancer Center, Davis, CA, USA.
Primo N LaraDepartment of Internal Medicine, UC Davis Comprehensive Cancer Center, Davis, CA, USA.
City Of Hope National Medical Center · USUC Davis Comprehensive Cancer CenterBeckman Research InstituteCity of Hope · USPenn State Milton S. Hershey Medical Center · USUniversity of California, Davis · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI PRIMO N. LARA · 2002 to 2026
$84.9M
Phase I Molecular and Clinical Pharmacodynamic Trials ETCTNUM1CA186717 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI A. Dimitrios Colevas, Alexey V. Danilov · 2014 to 2026
$19.8M
NCI NIH HHS P30 CA033572NCI NIH HHS P30 CA093373NCI NIH HHS UM1 CA186717
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CaliforniaHumansMyelodysplastic SyndromesReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsTreatment OutcomeafliberceptReceptors, Vascular Endothelial Growth FactorRecombinant Fusion Proteinsclinical trialsmyelodysplastic syndromevascular endothelial growth factor

Identifiers

PMID27650362
PMCPMC5360527
OpenAlexW2522868325

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.