ReviewLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society2017
Biliary atresia: Indications and timing of liver transplantation and optimization of pretransplant care.
Review in Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06260566 (A Phase 1 Trial of Tolerability of Enteral N-Acetylcysteine in Infants), which is not on this map. Cited by 119 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase 1 Trial of Tolerability of Enteral N-Acetylcysteine in Infants
Who cites it
119 citing papers in PubMed, 6 syntheses or guidelines pooled it, 249 citations in OpenAlex.
- Hypermanganesemia in Children With Liver and Portosystemic Circulation Disorders: A Systematic Review.Journal of paediatrics and child health · 2026Pooled it
- Serum predictors of native liver survival post-Kasai: Systematic review and meta-analysis.Journal of pediatric gastroenterology and nutrition · 2026Pooled it
- The diagnostic performance of ultrasound elastography for biliary atresia: A meta-analysis.Frontiers in public health · 2022Pooled it
- Laparoscopic vs open portoenterostomy in biliary atresia: a systematic review and meta-analysis.Pediatric surgery international · 2021Pooled it
- Clinical Practice Guidelines for Liver Transplantation in Saudi Arabia.Saudi medical journal · 2021Guideline
- Comparison of laparoscopic portoenterostomy and open portoenterostomy for the treatment of biliary atresia.Surgical endoscopy · 2019Pooled it
- A Phase I/IIa Trial of Intravenous Immunoglobulin Following Portoenterostomy in Biliary Atresia.Journal of pediatric gastroenterology and nutrition · 2019Trial
- LncRNA H19 as a key regulator in biliary atresia: insights into pathogenesis and potential therapeutic targets.Annals of medicine · 2026Review
- Diagnostic and management guidelines for biliary atresia in 2025.Hepatobiliary surgery and nutrition · 2026Review
- Effect of perioperative Sonoclot monitoring on early thrombosis after pediatric liver transplantation: a prospective observational study.Translational pediatrics · 2026Article
- Transfer learning prediction of 2-year native liver survival in biliary atresia following Kasai portoenterostomy using early perioperative biochemical data up to 3 months postoperatively.Pediatric surgery international · 2026Article
- Preoperative porta hepatis-to-hepatic surface ratio on 24-h delayed hepatobiliary scintigraphy is associated with jaundice clearance after Kasai portoenterostomy.Pediatric surgery international · 2026Article
- A nomogram for predicting early- and mid-term native liver survival after surgery in patients with type III biliary atresia: a single-center retrospective study.BMC surgery · 2026Article
- Early Living Donor Liver Transplant Is Associated With Improved Graft- and Patient-Survival Outcomes in Children With Biliary Atresia.Pediatric transplantation · 2026Article
- Long-term outcomes of liver transplantation in biliary atresia: a 20-year single-center study.Pediatric surgery international · 2026Article
- Hepatic blood flow velocity before and 3 months after Kasai portoenterostomy is a prognostic indicator for native liver survival in biliary atresia.European journal of pediatrics · 2026Article
- Dysregulation of Trace Elements in Pediatric Cholestasis: From Pathophysiology to Nutritional Approaches.International journal of molecular sciences · 2026Review
- A 23-Year Comprehensive Analysis of over 4000 Liver Transplants in Türkiye: Integrating Clinical Outcomes with Public Health Insights.Healthcare (Basel, Switzerland) · 2026Article
- Medium-chain triglyceride supplementation in infants with biliary atresia: a review of the evidence for impacts on fat absorption, growth, nutritional status and clinical outcomes.The Proceedings of the Nutrition Society · 2026Review
- Real-world use of maralixibat in biliary atresia: a case series.Frontiers in pediatrics · 2026Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Biliary atresia (BA) is a progressive, fibro-obliterative disorder of the intrahepatic and extrahepatic bile ducts in infancy. The majority of affected children will eventually develop end-stage liver disease and require liver transplantation (LT). Indications for LT in BA include failed Kasai portoenterostomy, significant and recalcitrant malnutrition, recurrent cholangitis, and the progressive manifestations of portal hypertension. Extrahepatic complications of this disease, such as hepatopulmonary syndrome and portopulmonary hypertension, are also indications for LT. Optimal pretransplant management of these potentially life-threatening complications and maximizing nutrition and growth require the expertise of a multidisciplinary team with experience caring for BA. The timing of transplant for BA requires careful consideration of the potential risk of transplant versus the survival benefit at any given stage of disease. Children with BA often experience long wait times for transplant unless exception points are granted to reflect severity of disease. Family preparedness for this arduous process is therefore critical. Liver Transplantation 23:96-109 2017 AASLD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.