ArticleStroke2016
Stroke Risk and Mortality in Patients With Ventricular Assist Devices.
Article in Stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 78 citations in OpenAlex.
- Embolic Transport in LVAD Outflow: An Experimental Study Using Patient-Specific and Idealized Aortic Models.Annals of biomedical engineering · 2026Article
- Gastrointestinal Bleeding During Long-Term Left Ventricular Assist Device Support: External Validation of UTAH Bleeding Risk Score.Journal of cardiovascular development and disease · 2025Article
- Outcomes of 576 patients with extracorporeal life support for the treatment of perioperative cardiogenic shock.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Quantitative Assessment of Aortic Hemodynamics for Varying Left Ventricular Assist Device Outflow Graft Angles and Flow Pulsation.Annals of biomedical engineering · 2023Article
- Neurologic Complications in Patients With Left Ventricular Assist Devices.The Canadian journal of cardiology · 2023Review
- Peripartum Cardiogenic Shock and Mechanical Circulatory Support.Interventional cardiology (London, England) · 2023Review
- Left Ventricular Assist Devices: A Primer For the General Cardiologist.Journal of the American Heart Association · 2022Review
- Implications of Causes of Intracranial Hemorrhage During Left Ventricular Assist Device Support.Neurocritical care · 2022Article
- Mechanical Thrombectomy for M1 Subocclusive Thrombus With Lateral Lenticulostriate Artery Occlusion: A Case Report and Literature Review.Frontiers in neurology · 2022Article
- Characteristics of strokes associated with centrifugal flow left ventricular assist devices.Scientific reports · 2021Article
- Gastrointestinal Bleeding as a Complication in Continuous Flow Ventricular Assist Devices: A Systematic Review With Meta-Analysis.Journal of clinical medicine research · 2020Article
- Association Between Heart Transplantation and Subsequent Risk of Stroke Among Patients With Heart Failure.Stroke · 2019Article
- Stroke Incidence and Impact of Continuous-Flow Left Ventricular Assist Devices on Cerebrovascular Physiology.Stroke · 2019Article
- Treatment course and outcomes after revascularization surgery for moyamoya disease in adults.Journal of neurology · 2018Article
- Antithrombotic therapy in ventricular assist device (VAD) management: From ancient beliefs to updated evidence. A narrative review.International journal of cardiology. Heart & vasculature · 2018Review
- Intermediate-Term Risk of Stroke Following Cardiac Procedures in a Nationally Representative Data Set.Journal of the American Heart Association · 2017Article
- Article
- Incidence and impact of ischemic and hemorrhagic stroke after left ventricular assist device implantation: A nationwide study.Indian heart journalArticle
- Risk Factors for Development of Stroke in Patients With Continuous-Flow Left Ventricular Assist Device Support as Destination Therapy.Texas Heart Institute journalArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
background and purposeVentricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these devices are associated with hemorrhagic and thrombotic complications, including stroke. We assessed the incidence, risk factors, and outcomes of ischemic and hemorrhagic stroke after VAD placement.
methodsUsing administrative claims data from acute care hospitals in California, Florida, and New York from 2005 to 2013, we identified patients who underwent VAD placement, defined by the International Classification of Diseases, Ninth Revision, Clinical Modification code 37.66. Ischemic and hemorrhagic strokes were identified by previously validated coding algorithms. We used survival statistics to determine the incidence rates and Cox proportional hazard analyses to examine the associations.
resultsAmong 1813 patients, we identified 201 ischemic strokes and 116 hemorrhagic strokes during 3.4 (±2.0) years of follow-up after implantation of a VAD. The incidence of stroke was 8.7% per year (95% confidence interval [CI], 7.7-9.7). The annual incidence of ischemic stroke (5.5%; 95% CI, 4.8-6.4) was nearly double that of hemorrhagic stroke (3.1%; 95% CI, 2.6-3.8). Women faced a higher hazard of stroke than men (hazard ratio, 1.6; 95% CI, 1.2-2.1), particularly hemorrhagic stroke (hazard ratio, 2.2; 95% CI, 1.4-3.4). Stroke was strongly associated with subsequent in-hospital mortality (hazard ratio, 6.1; 95% CI, 4.6-7.9).
conclusionsThe incidence of stroke after VAD implantation was 8.7% per year, and incident stroke was strongly associated with subsequent in-hospital mortality. Notably, ischemic stroke occurred at nearly twice the rate of hemorrhagic stroke. Women seemed to face a higher risk for hemorrhagic stroke than men.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.