Evidence map›Paper›PMID 27649986›Full record

ReviewDer Nervenarzt2016

[Cerebrospinal fluid diagnostics in multiple sclerosis].

K Ruprecht, H Tumani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

K RuprechtKlinik für Neurologie, Klinisches und Experimentelles Forschungszentrum für Multiple Sklerose, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
H TumaniFachklinik für Neurologie Dietenbronn, Dietenbronn 7, 88477, Schwendi, Deutschland. hayrettin.tumani@uni-ulm.de.
Charité - Universitätsmedizin Berlin · DEFachklinik für Neurologie Dietenbronn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a chronic inflammatory disease of the central nervous system (CNS), multiple sclerosis (MS) is associated with characteristic abnormalities in cerebrospinal fluid (CSF). Thus, in addition to magnetic resonance imaging, CSF examination is a central diagnostic procedure in patients with MS, which can corroborate a diagnosis of MS and may also help to discern differential diagnoses. The most important CSF finding in MS is the detection of persistent polyspecific intrathecal immunoglobulin synthesis. This review summarizes CSF findings of patients with MS and addresses issues of relevance for clinical practice, potential diagnostic pitfalls as well as new developments in CSF diagnostics of MS.

Indexed as

Diagnostic Techniques, NeurologicalBiomarkersCerebrospinal FluidHumansImmunoglobulinsMultiple SclerosisBiomarkersImmunoglobulinsCerebrospinal fluidDiagnosisDifferential diagnosisImmunoglobulinsOligoclonal bands

Identifiers

PMID27649986
OpenAlexW2526458153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.