ArticleLasers in medical science2017
Effect of low-level laser therapy on angiogenesis and matrix metalloproteinase-2 immunoexpression in wound repair.
Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03741062 (Effects of Er), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Er:YAG Photobiomodulation Therapy on Wound Healing of Human Palatal Mucosa After Connective Tissue Graft Harvesting: A Pilot Study
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Should open excisions and sutured incisions be treated differently? A review and meta-analysis of animal wound models following low-level laser therapy.Lasers in medical science · 2018Pooled it
- The Effect of Er:YAG Laser Therapy as an Adjunct to Surgical Treatment Compared to Latter Alone in Managing Medication-Related Osteonecrosis of the Jaw: A Randomised Controlled Clinical Trial.International dental journal · 2026Trial
- Free gingival graft adjunct with low-level laser therapy: a randomized placebo-controlled parallel group study.Clinical oral investigations · 2019Trial
- Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.Lasers in medical science · 2017Trial
- Effect of photobiomodulation and corticopuncture methods on tooth displacement and gene expression: animal study.Lasers in medical science · 2024Article
- Effects of photobiomodulation with blue Light Emitting Diode (LED) on the healing of skin burns.Lasers in medical science · 2023Article
- Influence of Three Laser Wavelengths with Different Power Densities on the Mitochondrial Activity of Human Gingival Fibroblasts in Cell Culture.Life (Basel, Switzerland) · 2023Article
- Activation of Wnt/β-Catenin Signaling Involves 660 nm Laser Radiation on Epithelium and Modulates Lipid Metabolism.Biomolecules · 2022Article
- Effects of photobiomodulation therapy with red LED on inflammatory cells during the healing of skin burns.Lasers in medical science · 2022Article
- An in-vivo study of photobiomodulation using 403 nm and 649 nm diode lasers for molar tooth extraction wound healing in wistar rats.Odontology · 2022Article
- Photobiomodulation reduces hippocampal apoptotic cell death and produces a Raman spectroscopic "signature".PloS one · 2022Article
- Area light source-triggered latent angiogenic molecular mechanisms intensify therapeutic efficacy of adult stem cells.Bioengineering & translational medicine · 2022Article
- Effect of NIR Laser Therapy by MLS-MiS Source on Fibroblast Activation by Inflammatory Cytokines in Relation to Wound Healing.Biomedicines · 2021Article
- Photobiomodulation alters the viability of HUVECs cells.Lasers in medical science · 2021Article
- Effect of Microgravity on Endothelial Cell Function, Angiogenesis, and Vessel Remodeling During Wound Healing.Frontiers in bioengineering and biotechnology · 2021Review
- The Combined Effect of Photobiomodulation and Curcumin on Acute Skin Wound Healing in Rats.Journal of lasers in medical sciences · 2021Article
- Effect of different low-level intensity laser therapy (LLLT) irradiation protocols on the osseointegration of implants placed in grafted areas.Journal of applied oral science : revista FOB · 2021Article
- Bicontinuous microemulsions containing Melaleuca alternifolia essential oil as a therapeutic agent for cutaneous wound healing.Drug delivery and translational research · 2020Article
- Evaluation of angiogenesis, inflammation, and healing on irradiated skin graft with low-level laser therapy in rats (Rattus norvegicus albinus wistar).Lasers in medical science · 2020Article
- Photobiomodulation of red and green lights in the repair process of third-degree skin burns.Lasers in medical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low-level laser therapy (LLLT) induces anti-inflammatory and angiogenic activities in wound healing. However, the mechanism of action and optimal parameters require further clarification. In this study, we investigated the effects of LLLT on wound healing matrix metalloproteinase (MMP)-2 immunoexpression and angiogenic processes. Twenty female Wistar rats were randomly divided into four groups (n = 5) according to the treatments as follows. CG7 and CG14 were control groups at days 7 and 14, respectively, which received physiological saline (0.9 % NaCl daily). LG7 and LG14 were laser therapy groups at days 7 and 14, respectively, which received two (LG7) or four (LG14) LLLT applications (40 mW; 660 nm; 4 J/cm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.