SynthesisEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2017
The application of sonication in diagnosis of periprosthetic joint infection.
Synthesis in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Sonication fluid culture of antibiotic-loaded bone cement spacer has high accuracy to confirm eradication of infection before reimplantation of new prostheses.Journal of orthopaedic surgery and research · 2021Pooled it
- Meta-analysis in periprosthetic joint infection: a global bibliometric analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Meta-analysis of sonication prosthetic fluid PCR for diagnosing periprosthetic joint infection.PloS one · 2018Pooled it
- Biofilm Removal and Bacterial Reduction Using a Low-Cost Ultrasonic Bath Sonicator with Povidone-Iodine on Polyethylene: An In Vitro Periprosthetic Joint Infection Model.Antibiotics (Basel, Switzerland) · 2026Article
- Review
- Quantification of Sonicated Implants from Patients with Osteoarticular Implant Infections.Antibiotics (Basel, Switzerland) · 2026Article
- Improved Microbiological Diagnosis of Bone and Joint Infections Using Mechanical Bead-Milling Extraction of Bone Specimens with the Ultra-TurraxDiagnostics (Basel, Switzerland) · 2026Article
- Utilization of cell-free DNA metagenomic analysis for early detection and microbial identification in prosthetic joint infections: a prospective cohort study in Korea.Frontiers in cellular and infection microbiology · 2025Article
- Improving the microbiological diagnosis of fracture-related infection and prosthetic joint infection through culturing sonication fluid in Bactec blood culture bottles.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Advancing Diagnostic Techniques for Implant-Related Infections: the Synergistic Effect of Sonication and Dithiothreitol.Maedica · 2024Article
- Evaluating the Clinical Relevance of Routine Sonication for Periprosthetic Hip or Knee Joint Infection Diagnosis.Antibiotics (Basel, Switzerland) · 2024Article
- Role of Dithiothreitol in Detection of Orthopaedic Implant-Associated Infections.Journal of personalized medicine · 2024Article
- Single-stage total hip arthroplasty after failed fixation of proximal femoral fractures: an increased risk for periprosthetic joint infections?Archives of orthopaedic and trauma surgery · 2022Article
- Sonication in the diagnosis of fracture-related infections (FRI)-a retrospective study on 230 retrieved implants.Journal of orthopaedic surgery and research · 2021Article
- Challenges in the Microbiological Diagnosis of Implant-Associated Infections: A Summary of the Current Knowledge.Frontiers in microbiology · 2021Review
- A comparative study of heterogeneous antibiotic resistance of microbial populations in conventional periprosthetic tissue cultures and sonication fluid cultures of orthopaedics explanted prostheses.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Article
- Improved pre-operative diagnostic accuracy for low-grade prosthetic joint infections using second-generation multiplex Polymerase chain reaction on joint fluid aspirate.International orthopaedics · 2020Article
- Sonication of retrieved implants improves sensitivity in the diagnosis of periprosthetic joint infection.BMC musculoskeletal disorders · 2019Article
- Culture-negative periprosthetic joint infections.EFORT open reviews · 2019Review
- Culturing periprosthetic tissue in blood culture bottles results in isolation of additional microorganisms.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic joint infection (PJI) is a catastrophic complication after total joint arthroplasty. It has always been difficult to diagnose PJI, which is characterised by existence of biofilm around the implants. The application of sonication has proven advantageous for pathogen detection. This meta-analysis of clinical trials was performed to evaluate the diagnostic value of sonication and to compare it with traditional bacterial culture. We assessed 16 studies that evaluated sonication fluid cultures (SFC) for the diagnosis of PJI. It was shown that sonication may be of great value in PJI diagnosis, with a pooled sensitivity of 0.79 (95 % confidence interval [CI] = 0.76-0.81), specificity of 0.95 (CI = 0.94-0.96), DOR of 71.20 (CI = 31.08-163.10), PLR of 15.25 (CI = 6.44-36.15), and NLR of 0.23 (CI = 0.18-0.30). The AUC value of the SROC was 0.90. The results of this meta-analysis showed that culture of fluid after sonication was of great value for PJI diagnosis. Sonication was more sensitive than traditional tissue culture with lower specificity, especially for patients previously taking antibiotics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.