Evidence map›Paper›PMID 27649262›Full record

ArticleEmerging infectious diseases2016

Whole-Genome Characterization of Epidemic Neisseria meningitidis Serogroup C and Resurgence of Serogroup W, Niger, 2015.

Cecilia B Kretz, Adam C Retchless, Fati Sidikou, Bassira Issaka, Sani Ousmane, Stephanie Schwartz, Ashley H Tate, Assimawè Pana, Berthe-Marie Njanpop-Lafourcade, Innocent Nzeyimana and 12 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Genomic surveillance of invasive Neisseria meningitidis isolates circulating in Paraguay, 2009-2021.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The epidemiology of invasive meningococcal disease and the utility of vaccination in Malta.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Invasive Meningococcal Disease due to NongroupableOpen forum infectious diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Cecilia B Kretz
Adam C Retchless
Fati Sidikou
Bassira Issaka
Sani Ousmane
Stephanie Schwartz
Ashley H Tate
Assimawè Pana
Berthe-Marie Njanpop-Lafourcade
Innocent Nzeyimana
Ricardo Obama Nse
Ala-Eddine Deghmane
Eva Hong
Ola Brønstad Brynildsrud
Ryan T Novak
Sarah A Meyer
Odile Ouwe Missi Oukem-Boyer
Olivier Ronveaux
Dominique A Caugant
Muhamed-Kheir Taha
Xin Wang
Niger Response Team

Funding

CDC HHS
6 · The paper itself

Abstract

In 2015, Niger reported the largest epidemic of Neisseria meningitidis serogroup C (NmC) meningitis in sub-Saharan Africa. The NmC epidemic coincided with serogroup W (NmW) cases during the epidemic season, resulting in a total of 9,367 meningococcal cases through June 2015. To clarify the phylogenetic association, genetic evolution, and antibiotic determinants of the meningococcal strains in Niger, we sequenced the genomes of 102 isolates from this epidemic, comprising 81 NmC and 21 NmW isolates. The genomes of 82 isolates were completed, and all 102 were included in the analysis. All NmC isolates had sequence type 10217, which caused the outbreaks in Nigeria during 2013-2014 and for which a clonal complex has not yet been defined. The NmC isolates from Niger were substantially different from other NmC isolates collected globally. All NmW isolates belonged to clonal complex 11 and were closely related to the isolates causing recent outbreaks in Africa.

Indexed as

Genome, BacterialAntigens, BacterialCommunicable Diseases, EmergingDNA, BacterialDrug Resistance, BacterialEpidemicsGenetic VariationHumansMeningitis, MeningococcalMolecular TypingNeisseria meningitidisNeisseria meningitidis, Serogroup CNigerPhylogenySequence Analysis, DNASerotypingAntigens, BacterialDNA, Bacterialbacteriameningitis beltMeningococcal meningitisNeisseria meningitidis serogroup CNigerwhole-genome sequencing

Identifiers

PMID27649262
PMCPMC5038424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.