Evidence map›Paper›PMID 27649147›Full record

ReviewInternational journal of molecular sciences2016

Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches.

Xi-Feng Zhang, Zhi-Guo Liu, Wei Shen, Sangiliyandi Gurunathan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 800 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
800citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

800 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparison of retention rates of silver nanoparticles-based fissure sealant and conventional resin-based sealant: a one-year randomized clinical trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
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  12. Eco-Friendly Synthesis of Silver Nanoparticles UsingInternational journal of molecular sciences · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Green-SynthesizedJournal of functional biomaterials · 2026
    Article
  20. Article

740 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xi-Feng ZhangCollege of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan 430023, China. zhangxf9465@163.com.
Zhi-Guo LiuCollege of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan 430023, China. zhiguo_l@126.com.
Wei ShenKey Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China. shenwei427@126.com.
Sangiliyandi GurunathanDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea. gsangiliyandi@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. AgNPs play an important role in nanoscience and nanotechnology, particularly in nanomedicine. Although several noble metals have been used for various purposes, AgNPs have been focused on potential applications in cancer diagnosis and therapy. In this review, we discuss the synthesis of AgNPs using physical, chemical, and biological methods. We also discuss the properties of AgNPs and methods for their characterization. More importantly, we extensively discuss the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti-cancer activity of AgNPs. In addition, we discuss therapeutic approaches and challenges for cancer therapy using AgNPs. Finally, we conclude by discussing the future perspective of AgNPs.

Indexed as

Angiogenesis InhibitorsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic AgentsGreen Chemistry TechnologyHumansMetal NanoparticlesSilverAngiogenesis InhibitorsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic AgentsSilverapplicationscancer therapycharacterizationmechanismssilver nanoparticlessynthesis

Identifiers

PMID27649147
PMCPMC5037809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.