Evidence map›Paper›PMID 27649134›Full record

ArticleMolecules (Basel, Switzerland)2016

Chemical Constituents from Flueggea virosa and the Structural Revision of Dehydrochebulic Acid Trimethyl Ester.

Chih-Hua Chao, Ying-Ju Lin, Ju-Chien Cheng, Hui-Chi Huang, Yung-Ju Yeh, Tian-Shung Wu, Syh-Yuan Hwang, Yang-Chang Wu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Development and validation of UPLC-PDA method for concurrent analysis of bergenin and menisdaurin in aerial parts ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chih-Hua ChaoSchool of Pharmacy, China Medical University, Taichung 40402, Taiwan. chaochihhua@hotmail.com.
Ying-Ju LinSchool of Chinese Medicine, China Medical University, Taichung 40402, Taiwan. yjlin@mail.cmu.edu.tw.
Ju-Chien ChengDepartment of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan. jccheng@mail.cmu.edu.tw.
Hui-Chi HuangDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 40402, Taiwan. hchuang@mail.cmu.edu.tw.
Yung-Ju YehDepartment of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan. star740101@gmail.com.
Tian-Shung WuDepartment of Pharmacy, National Cheng Kung University, Tainan 70101, Taiwan. tswu@mail.ncku.edu.tw.
Syh-Yuan HwangEndemic Species Research Institute, Council of Agriculture, Nantou 55244, Taiwan. son757780@yahoo.com.tw.
Yang-Chang WuSchool of Pharmacy, China Medical University, Taichung 40402, Taiwan. yachwu@mail.cmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an attempt to study the chemical constituents from the twigs and leaves of Flueggea virosa, a new terpenoid, 9(10→20)-abeo-ent-podocarpane, 3β,10α-dihydroxy-12-methoxy-13- methyl-9(10→20)-abeo-ent-podocarpa-6,8,11,13-tetraene (1), as well as five known compounds were characterized. Their structures were elucidated on the basis of spectroscopic analysis. In addition, the structure of dehydrochebulic acid trimethyl ester was revised as (2S,3R)-4E-dehydrochebulic acid trimethyl ester based on a single-crystal X-ray diffraction study. The in vitro anti-hepatitis C virus (anti-HCV) activity and cytotoxicity against Huh7.5 cells for the isolated compounds were evaluated.

Indexed as

Antiviral AgentsBenzopyransHepacivirusMaleatesCell LineEuphorbiaceaeHepatitis CHumansPlant RootsAntiviral AgentsBenzopyransdehydrochebulic acid trimethyl esterMaleatesanti-HCVdehydrochebulic acid trimethyl esterent-podocarpaneFlueggea virosaHCVcc

Identifiers

PMID27649134
PMCPMC6274521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.