ArticleThe ISME journal2017
Phylogenomic networks reveal limited phylogenetic range of lateral gene transfer by transduction.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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Who cites it
49 citing papers in PubMed, 117 citations in OpenAlex.
- The interplay between ecological networks drives host-plasmid community dynamics.PLoS computational biology · 2026Article
- Diversity, transfer potential, and transcriptional activity of virus-carried antibiotic resistance genes in global estuaries.iMetaOmics · 2026Article
- Diverse Temperate Coliphages of the Urinary Tract.Viruses · 2026Article
- Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny.The ISME journal · 2026Article
- Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny.bioRxiv : the preprint server for biology · 2025Article
- Extensive data mining uncovers novel diversity among members of the rare biosphere within the Thermoplasmatota.Microbiome · 2025Article
- Starship giant transposable elements cluster by host taxonomy using k-mer-based phylogenetics.G3 (Bethesda, Md.) · 2025Article
- Gut phages and their interactions with bacterial and mammalian hosts.Journal of bacteriology · 2025Review
- Diversity and evolution of prokaryotic viral lytic proteins.The ISME journal · 2025Article
- A global survey of prokaryotic genomes reveals the eco-evolutionary pressures driving horizontal gene transfer.Nature ecology & evolution · 2024Article
- Bacterial defense systems exhibit synergistic anti-phage activity.Cell host & microbe · 2024Article
- Article
- Tailless and filamentous prophages are predominant in marine Vibrio.The ISME journal · 2024Article
- Breaking the Ice: A Review of Phages in Polar Ecosystems.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Genome-wide transformation reveals extensive exchange across closely related Bacillus species.Nucleic acids research · 2023Article
- Comparative Genomics ofPHAGE (New Rochelle, N.Y.) · 2023Article
- Distribution of fitness effects of cross-species transformation reveals potential for fast adaptive evolution.The ISME journal · 2023Article
- Associations between picocyanobacterial ecotypes and cyanophage host genes across ocean basins and depth.PeerJ · 2023Article
- Mining of Thousands of Prokaryotic Genomes Reveals High Abundance of Prophages with a Strictly Narrow Host Range.mSystems · 2022Article
- What makes a megaplasmid?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Bacteriophages are recognized DNA vectors and transduction is considered as a common mechanism of lateral gene transfer (LGT) during microbial evolution. Anecdotal events of phage-mediated gene transfer were studied extensively, however, a coherent evolutionary viewpoint of LGT by transduction, its extent and characteristics, is still lacking. Here we report a large-scale evolutionary reconstruction of transduction events in 3982 genomes. We inferred 17 158 recent transduction events linking donors, phages and recipients into a phylogenomic transduction network view. We find that LGT by transduction is mostly restricted to closely related donors and recipients. Furthermore, a substantial number of the transduction events (9%) are best described as gene duplications that are mediated by mobile DNA vectors. We propose to distinguish this type of paralogy by the term autology. A comparison of donor and recipient genomes revealed that genome similarity is a superior predictor of species connectivity in the network in comparison to common habitat. This indicates that genetic similarity, rather than ecological opportunity, is a driver of successful transduction during microbial evolution. A striking difference in the connectivity pattern of donors and recipients shows that while lysogenic interactions are highly species-specific, the host range for lytic phage infections can be much wider, serving to connect dense clusters of closely related species. Our results thus demonstrate that DNA transfer via transduction occurs within the context of phage-host specificity, but that this tight constraint can be breached, on rare occasions, to produce long-range LGTs of profound evolutionary consequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.