Evidence map›Paper›PMID 27648804›Full record

ReviewJournal of neurosurgical anesthesiology2017

Hypertension After Severe Traumatic Brain Injury: Friend or Foe?

Vijay Krishnamoorthy, Nophanan Chaikittisilpa, Taniga Kiatchai, Monica Vavilala

Abstract readReview
In one paragraph

Review in Journal of neurosurgical anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Observational
  5. Effects of early propranolol administration on mortality from severe, traumatic brain injury: a retrospective propensity score-matched registry study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Eight rules for the haemodynamic management of traumatic brain-injured patients.European journal of anaesthesiology and intensive care · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vijay Krishnamoorthy*Department of Anesthesiology and Pain Medicine, University of Washington †Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA.
Nophanan Chaikittisilpa
Taniga Kiatchai
Monica Vavilala

Funding

Anesthesiology & Perioperative Medicine Training GrantT32GM086270 · NIGMS · UNIVERSITY OF WASHINGTON · PI Tonya M Palermo · 2009 to 2026
$4.3M
NIGMS NIH HHS T32 GM086270NINDS NIH HHS L30 NS084420
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a major public health problem, with severe TBI contributing to a large number of deaths and disability worldwide. Early hypotension has been linked with poor outcomes following severe TBI, and guidelines suggest early and aggressive management of hypotension after TBI. Despite these recommendations, no guidelines exist for the management of hypertension after severe TBI, although observational data suggests that early hypertension is also associated with an increased risk of mortality after severe TBI. The purpose of this review is to discuss the underlying pathophysiology of hypertension after TBI, provide an overview of the current clinical data on early hypertension after TBI, and discuss future research that should test the benefits and harms of treating high blood pressure in TBI patients.

Indexed as

Brain Injuries, TraumaticCatecholaminesHumansHypertensionCatecholamines

Identifiers

PMID27648804
PMCPMC5357208

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.