Evidence map›Paper›PMID 27648637›Full record

ArticlePharmacogenomics2016

Patient experiences with pharmacogenetic testing in a primary care setting.

Susanne B Haga, Rachel Mills, Jivan Moaddeb, Nancy Allen Lapointe, Alex Cho, Geoffrey S Ginsburg

Abstract read
In one paragraph

Article in Pharmacogenomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susanne B HagaCenter for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Rachel MillsCenter for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Jivan MoaddebCenter for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Nancy Allen LapointeDuke Clinical Research Institute, Duke University, Durham, NC 22708, USA.
Alex ChoCenter for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Geoffrey S GinsburgCenter for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.

Funding

Pharmacogenetic Testing: Challenges of Clinical IntegrationR01GM081416 · NIGMS · DUKE UNIVERSITY · PI HAGA, SUSANNE · 2008 to 2018
$4.6M
NIGMS NIH HHS R01 GM081416
6 · The paper itself

Abstract

aimTo investigate patient experiences with pharmacogenetic (PGx) testing.

methodsPatients were offered PGx testing through a study on pharmacist-assisted delivery of PGx testing and invited to complete pre- and post-testing surveys about their experience.

resultsOf 63 patients tested, 17 completed the baseline survey (27%). Interest in testing was mostly impacted by desire to inform selection of best treatment (n = 13). Seven of 12 patients that completed the follow-up survey indicated that their provider discussed the test result with them. Five patients understood their test result very or somewhat well. All would be likely to have PGx testing again.

conclusionPatients perceived PGx testing to be useful, though more effort may be needed to improve patient-provider communication of test results.

Indexed as

Pharmacogenomic TestingPrimary Health CareAdultAgedCommunicationFemaleHumansMaleMiddle AgedPhysician-Patient Relations

Identifiers

PMID27648637
PMCPMC5558503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.