Evidence map›Paper›PMID 27648590›Full record

SynthesisThe Clinical journal of pain2017

A Systematic Review and Meta-Analysis of Migraine and Suicidal Ideation.

Lauren E Friedman, Bizu Gelaye, Paul A Bain, Michelle A Williams

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Clinical journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  3. Trial
  4. Psychoneuroimmunology: The new frontier in suicide research.Brain, behavior, & immunity - health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lauren E Friedman*Department of Epidemiology, Harvard T. H. Chan School of Public Health †Harvard Medical School, Countway Library of Medicine, Boston, MA.
Bizu Gelaye
Paul A Bain
Michelle A Williams
Harvard University · US

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
NICHD NIH HHS R01 HD059835NIMHD NIH HHS T37 MD001449
6 · The paper itself

Abstract

backgroundPrevious studies have demonstrated an association between migraine and major depressive disorder. However, relatively little is known about the relationship between suicidal ideation, with or without concurrent depression, and migraine.

objectiveWe conducted a systematic literature review to synthesize the available research focused on investigating the association of migraine with suicidal ideation.

methodsRelevant research papers were identified through searches of major electronic databases including PubMed, Embase (Elsevier), Web of Science (Thomson Reuters), PsycINFO (EBSCO), and Google Scholar. We performed a meta-analysis to estimate the pooled unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (95% CI) for the association between migraine and suicidal ideation extracted from each study.

resultsA total of 148,977 participants in 6 studies were included in this analysis. Overall, findings from available studies documented elevated odds of suicidal ideation among individuals with migraines. In unadjusted models, the odds of suicidal ideation was 2.49-fold higher among individuals with migraine (OR, 2.49; 95% CI, 2.34-2.65) compared with those without migraine. In multivariate-adjusted models, the pooled adjusted OR of suicidal ideation was 1.31 (OR, 1.31; 95% CI, 1.10-1.55).

conclusionsA meta-analysis of available studies suggests a modest positive association between migraine and suicidal ideation. Further studies allowing for a more comprehensive investigation of the association between migraine and the full range of suicidal behaviors are warranted. A larger and more robust evidence-base may be useful to inform the clinical screening and diagnoses of comorbid conditions in migraineurs.

Indexed as

Suicidal IdeationDatabases, BibliographicHumansMigraine Disorders

Identifiers

PMID27648590
PMCPMC5357206
OpenAlexW2520665506

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.