Evidence map›Paper›PMID 27648425›Full record

ArticleIranian journal of public health2016

Prevalence of Virulence Factors and Vancomycin-resistant Genes among Enterococcus faecalis and E. faecium Isolated from Clinical Specimens.

Mona Nasaj, Seyed Masoud Mousavi, Seyed Mostafa Hosseini, Mohammad Reza Arabestani

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Article in Iranian journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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25citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Rapid Detection ofBioMed research international · 2022
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  18. Article
  19. Antimicrobial Resistance and Virulence Genes inBioMed research international · 2019
    Article
  20. Molecular Characterization Of Vancomycin-ResistantInfection and drug resistance · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mona NasajDept. of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Seyed Masoud MousaviDept. of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Seyed Mostafa HosseiniDept. of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Mohammad Reza ArabestaniDept. of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the occurrence of virulence determinants and vancomycin-resistant genes among Enterococcus faecalis and E. faecium obtained from various clinical sources.

methodsThe study was performed on the 280 enterococcal isolated from clinical specimens in Hamadan hospitals, western Iran in 2012-14. Antibiotic susceptibility testing was performed using disk diffusion and Minimal Inhibitory Concentration (MIC) methods. The presence of vancomycin-resistant genes and virulence genes was investigated using PCR.

resultsTotally 280 enterococcal isolates were identified as follows: E. faecalis (62.5%), E. faecium (24%) and Enterococcus spp (13.5%). The results of antibiotic susceptibility testing showed that resistance rates to vancomycin and teicoplanin in E. faecalis and E. faecium isolates were 5% and 73%, respectively. Of Sixty vancomycin-resistant Enterococci strains, fifty-one isolates were identified as E. faecium (VREfm) and nine as E. faecalis (VREfs). Prevalence of esp, hyl, and asa1 genes were determined as 82%, 71.6%, and 100%, respectively in E. faecium strains; and 78%, 56/6%, and 97%, respectively in E. faecalis strains.

conclusionThe increased frequency of VREF, as seen with rapid rise in the number of vanA isolates should be considered in infection control practices.

Indexed as

E. faecalisE. faeciumMinimum inhibitory concentrationVancomycin-resistant enterococci

Identifiers

PMID27648425
PMCPMC5026837

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.