Evidence map›Paper›PMID 27648327›Full record

ArticleCase reports in orthopedics2016

Resection and Resolution of Bone Marrow Lesions Associated with an Improvement of Pain after Total Knee Replacement: A Novel Case Study Using a 3-Tesla Metal Artefact Reduction MRI Sequence.

Thomas Kurien, Robert Kerslake, Brett Haywood, Richard G Pearson, Brigitte E Scammell

Abstract read
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Article in Case reports in orthopedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Thomas KurienArthritis Research UK Pain Centre, Nottingham University, Nottingham, UK; Academic Orthopaedics, Trauma and Sports Medicine, School of Medicine, The University of Nottingham, Queen's Medical Centre, Derby Road, Nottingham NG7 2UH, UK.ORCID 0000-0003-0370-3150
Robert KerslakeArthritis Research UK Pain Centre, Nottingham University, Nottingham, UK; Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.ORCID 0000-0002-3694-2345
Brett HaywoodArthritis Research UK Pain Centre, Nottingham University, Nottingham, UK; Academic Radiology, The University of Nottingham, Queen's Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Richard G PearsonArthritis Research UK Pain Centre, Nottingham University, Nottingham, UK; Academic Orthopaedics, Trauma and Sports Medicine, School of Medicine, The University of Nottingham, Queen's Medical Centre, Derby Road, Nottingham NG7 2UH, UK.
Brigitte E ScammellArthritis Research UK Pain Centre, Nottingham University, Nottingham, UK; Academic Orthopaedics, Trauma and Sports Medicine, School of Medicine, The University of Nottingham, Queen's Medical Centre, Derby Road, Nottingham NG7 2UH, UK; Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham NG7 2UH, UK.

Funding

Medical Research Council MR/L017245/1
6 · The paper itself

Abstract

We present our case report using a novel metal artefact reduction magnetic resonance imaging (MRI) sequence to observe resolution of subchondral bone marrow lesions (BMLs), which are strongly associated with pain, in a patient after total knee replacement surgery. Large BMLs were seen preoperatively on the 3-Tesla MRI scans in a patient with severe end stage OA awaiting total knee replacement surgery. Twelve months after surgery, using a novel metal artefact reduction MRI sequence, we were able to visualize the bone-prosthesis interface and found complete resection and resolution of these BMLs. This is the first reported study in the UK to use this metal artefact reduction MRI sequence at 3-Tesla showing that resection and resolution of BMLs in this patient were associated with an improvement of pain and function after total knee replacement surgery. In this case it was associated with a clinically significant improvement of pain and function after surgery. Failure to eradicate these lesions may be a cause of persistent postoperative pain that is seen in up to 20% of patients following TKR surgery.

Identifiers

PMID27648327
PMCPMC5014972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.