Evidence map›Paper›PMID 27648171›Full record

ArticleIranian journal of neurology2016

A combined exercise model for improving muscle strength, balance, walking distance, and motor agility in multiple sclerosis patients: A randomized clinical trial.

Bahram Sangelaji, Mohammadreza Kordi, Farzaneh Banihashemi, Seyed Massood Nabavi, Sara Khodadadeh, Maryam Dastoorpoor

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  12. The Sit-to-Stand Transition as a Biomarker for Impairment: Comparison of Instrumented 30-Second Chair Stand Test and Daily Life Transitions in Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bahram SangelajiDepartment of Physiotherapy, School of Physiotherapy, Otago University, Dunedin, New Zealand AND Iranian Multiple Sclerosis Society Rehabilitation Centre, Tehran, Iran.
Mohammadreza KordiDepartment of Exercise Physiology, School of Physical ‎Education and Sport Sciences, University of Tehran, Tehran, Iran.
Farzaneh BanihashemiMother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Seyed Massood NabaviDepartment of Neurology, School of Medicine, Mostafa Khomeini Hospital, Shahed University of Medical Sciences, Tehran, Iran.
Sara KhodadadehDepartment of Exercise Physiology, School of Physical ‎Education and Sport Sciences, University of Tehran, Tehran, Iran.
Maryam DastoorpoorModeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Hormozgan University of Medical Sciences · IRKerman University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple sclerosis (MS) is a neurological disease with a variety of signs and symptoms. Exercise therapy has been shown to improve physical functions in MS. However, questions about an optimal exercise therapy remain. In this regard, we suggest a combined exercise therapy including aerobic and resistance exercises for MS patients. The study is designed to observe, test and compare the effects of proposed combined exercises on strength, balance, agility, fatigue, speed, and walking distance in people with mild to moderate MS [0 < expanded disability status scale (EDSS) < 5].

methodsA total of 40 people with relapse-remitting MS (16 male, 0 < EDSS < 5) were randomized into one of the four groups (3 intervention and one control). The intervention consisted of various combinations of aerobic and resistance exercises with different repetition rates. Pre- and post-intervention scores of fatigue severity scale (FSS), timed up and go (TUG) test, 6-minute walk test (6MWT), 10- and 20-MWT, Berg balance scale (BBS), and one repetition maximum (1RM) test were recorded and analyzed.

resultsFor most tests, post-intervention values of the group 1, with 3-aerobic and 1-resistance exercises, were significantly higher compared to control group (P < 0.050). However, no significant progression was observed in the other two intervention groups.

conclusionA combination of three aerobic exercises with one resistance exercise may result in improved balance, locomotion, and endurance in MS patients.

Indexed as

Aerobic ExerciseExercise TherapyMultiple SclerosisResistance Training

Identifiers

PMID27648171
PMCPMC5027145
OpenAlexW2472910736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.