Evidence map›Paper›PMID 27647855›Full record

Trial reportJournal of the American Society of Nephrology : JASN2017

Anti-TGF-

James Voelker, Paul H Berg, Matthew Sheetz, Kevin Duffin, Tong Shen, Brian Moser, Tom Greene, Samuel S Blumenthal, Ivan Rychlik, Yoram Yagil and 2 more

Abstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 1 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 1 synthesis or guideline pooled it, 267 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Article
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  19. Endothelial to mesenchymal transition: a central mechanism in diabetes-induced vascular pathology.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Review
  20. Inhibition of eCIRP attenuates PANoptosis and renal fibrosis.American journal of physiology. Renal physiology · 2025
    Article

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

James VoelkerLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana; voelker_james_r@lilly.com.
Paul H BergLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Matthew SheetzLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Kevin DuffinLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Tong ShenLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Brian MoserLilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Tom GreeneDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah.
Samuel S BlumenthalDepartment of Medicine, Zablocki Veterans Administration Medical Center, Milwaukee, Wisconsin.
Ivan RychlikSecond Department of Medicine, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Yoram YagilBarzilai University Medical Center, Department of Nephrology and Hypertension, Ashkelon and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheba, Israel.
Philippe ZaouiClinique Universitaire de Néphrologie, Centre Hospitalier Universitaire de Grenoble Alpes, Grenoble, France; and.
Julia B LewisDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Eli Lilly (United States) · USBen-Gurion University of the Negev · ILCharles University · CZMilwaukee VA Medical Center · USUniversité Grenoble Alpes · FRUniversity of Utah · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TGF-

Indexed as

Antibodies, MonoclonalDiabetic NephropathiesDouble-Blind MethodFemaleHumansMaleMiddle AgedTransforming Growth Factor beta1Antibodies, MonoclonalTransforming Growth Factor beta1Diabetic Kidney Diseaseproteinuriarenal fibrosisTransforming growth factor beta

Identifiers

PMID27647855
PMCPMC5328150
OpenAlexW2521123529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.