Evidence map›Paper›PMID 27647786›Full record

ArticleChembiochem : a European journal of chemical biology2016

Light-Activated Triazabutadienes for the Modification of a Viral Surface.

Stephanie M Jensen, Flora W Kimani, John C Jewett

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Crystal structure and spectroscopic properties of (Acta crystallographica. Section E, Crystallographic communications · 2021
    Article
  7. Coumarin Triazabutadienes for Fluorescent Labeling of Proteins.Chembiochem : a European journal of chemical biology · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephanie M JensenDepartment of Chemistry and Biochemistry, University of Arizona, Building 41, Room 104, 1306 E University Boulevard, Tucson, AZ, 85721, USA.
Flora W KimaniDepartment of Chemistry and Biochemistry, University of Arizona, Building 41, Room 104, 1306 E University Boulevard, Tucson, AZ, 85721, USA.
John C JewettDepartment of Chemistry and Biochemistry, University of Arizona, Building 41, Room 104, 1306 E University Boulevard, Tucson, AZ, 85721, USA.ORCID 0000-0001-5822-4080

Funding

CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
Radiation and Fluorescence Imaging Technology for Biology and BiochemistryS10OD013237 · OD · UNIVERSITY OF ARIZONA · PI PARK, CHAD KING · 2013 to 2013
$137k
NIGMS NIH HHS T32 GM008804NIH HHS S10 OD013237
6 · The paper itself

Abstract

Chemical crosslinking is a versatile tool for the examination of biochemical interactions, in particular host-pathogen interactions. We report the critical first step toward the goal of probing these interactions by the synthesis and use of a new heterobifunctional crosslinker containing a triazabutadiene scaffold. The triazabutadiene is stable to protein conjugation and liberates a reactive aryl diazonium species upon irradiation with 350 nm light. We highlight the use of this technology by modifying the surface of several proteins, including the dengue virus envelope protein.

Indexed as

Ultraviolet RaysButadienesCross-Linking ReagentsDengue VirusMolecular StructureSurface PropertiesViral Envelope ProteinsButadienesCross-Linking ReagentsViral Envelope Proteinsaryl diazonium ionbioconjugationcrosslinkingphotochemistryviruses

Identifiers

PMID27647786
PMCPMC5170875

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.