Evidence map›Paper›PMID 27647578›Full record

ReviewNeurogastroenterology and motility2017

Exploring hypotheses and rationale for causes of infantile colic.

M Camilleri, S-Y Park, E Scarpato, A Staiano

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neurogastroenterology and motility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Dietary modifications for infantile colic.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Trial
  3. Nutrients · 2020
    Trial
  4. Trial
  5. Observational
  6. Observational
  7. Frontiers in pediatrics · 2023
    Article
  8. Article
  9. Incidence and Associated Factors of Infantile Colic in Thai Infants.Pediatric gastroenterology, hepatology & nutrition · 2022
    Article
  10. The effect of symbiotic in the treatment of infantile colic: A double-blind, randomized, placebo-controlled clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  11. Review
  12. Review
  13. To learn, to remember, to forget-How smart is the gut?Acta physiologica (Oxford, England) · 2020
    Review
  14. Observational
  15. Infant colic: mechanisms and management.Nature reviews. Gastroenterology & hepatology · 2018
    Review
  16. Preterm Stress Behaviors, Autonomic Indices, and Maternal Perceptions of Infant Colic.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2018
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

M CamilleriClinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
S-Y ParkClinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
E ScarpatoDepartment of Translational Medical Science, Section of Pediatrics, University "Federico II", Naples, Italy.
A StaianoDepartment of Translational Medical Science, Section of Pediatrics, University "Federico II", Naples, Italy.
Federico II University Hospital · ITMayo Clinic in Arizona · US

Funding

Bile Acids, Genetic Control and Colonic Function in Irritable Bowel SyndromeR01DK092179 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2011 to 2015
$1.8M
NIDDK NIH HHS R01 DK092179
6 · The paper itself

Abstract

backgroundInfantile colic is a frequent problem in neonates and infants. This review addresses current management including the results for nutrient modifications; soy-based formulas; and prebiotics, probiotics, and synbiotics. PURPOSE: Given the evidence that there is still an unmet clinical need, as current treatments are incompletely efficacious, we have examined the evidence around three hypothetical mechanisms that could potentially be involved in etiopathogenesis of infantile colic: immaturity of bile acid mechanisms that alter intraluminal and absorptive mechanisms, immaturity in motility and alterations in the microbiome. Understanding these potential mechanisms may lead to the introduction of diagnostic procedures that should enhance the selection or individualization of therapy for infantile colic.

Indexed as

ColicHumansInfantInfant, NewbornPrebioticsProbioticsSynbioticsPrebioticsformulasnutritionprebioticsprobioticssynbiotics

Identifiers

PMID27647578
PMCPMC5276723
OpenAlexW2522299034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.