ArticleJournal of neurointerventional surgery2017
Selection of helical braided flow diverter stents based on hemodynamic performance and mechanical properties.
Article in Journal of neurointerventional surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Hemodynamics in Cerebral Aneurysms and Parent Arteries With Incompletely Expanded Flow Diverter Stents.International journal for numerical methods in biomedical engineering · 2025Article
- Determining flow stasis zones in the intracranial aneurysms and the relation between these zones and aneurysms' aspect ratios after flow diversions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Optimization of braided stent design for cerebral aneurysms: the role of wire cross-sectional geometry.Frontiers in bioengineering and biotechnology · 2025Article
- Comparison of Flow Reduction Efficacy of Nominal and Oversized Flow Diverters Using a Novel Measurement-assisted in Silico Method.Clinical neuroradiology · 2024Article
- Fluid dynamics in intracranial aneurysms treated with flow-diverting stents: effect of multiple geometrical parameters.Journal of fluid mechanics · 2023Article
- Global tendencies and frontier topics in hemodynamics research of intracranial aneurysms: a bibliometric analysis from 1999 to 2022.Frontiers in physiology · 2023Article
- Outcomes following aneurysmal coil embolization with intentionally shortened low-profile visible intraluminal support stent deployment.The neuroradiology journal · 2022Article
- Parent Artery Straightening after Flow-Diverter Stenting Improves the Odds of Aneurysm Occlusion.AJNR. American journal of neuroradiology · 2022Article
- Hemodynamic Investigation of the Effectiveness of a Two Overlapping Flow Diverter Configuration for Cerebral Aneurysm Treatment.Bioengineering (Basel, Switzerland) · 2021Article
- Computational Study of Hemodynamic Changes Induced by Overlapping and Compacting of Stents and Flow Diverter in Cerebral Aneurysms.Frontiers in neurology · 2021Article
- Possibility of Worsening Flow Diversion Effect Due to Morphological Changes of a Stented Artery With Multiple Overlapping Stents for Partially Thrombosed Vertebral Artery Aneurysms.Frontiers in neurology · 2020Article
- In vitro angiographic comparison of the flow-diversion performance of five neurovascular stents.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2018Article
- Phase-contrast MRI versus numerical simulation to quantify hemodynamical changes in cerebral aneurysms after flow diverter treatment.PloS one · 2018Article
- Computational Fluid Dynamics and Additive Manufacturing to Diagnose and Treat Cardiovascular Disease.Trends in biotechnology · 2017Review
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9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough flow diversion is a promising procedure for the treatment of aneurysms, complications have been reported and it remains poorly understood. The occurrence of adverse outcomes is known to depend on both the mechanical properties and flow reduction effects of the flow diverter stent.
objectiveTo clarify the possibility of designing a flow diverter stent considering both hemodynamic performance and mechanical properties. MATERIALS AND
methodsComputational fluid dynamics (CFD) simulations were conducted based on an ideal aneurysm model with flow diverters. Structural analyses of two flow diverter models exhibiting similar flow reduction effects were performed, and the radial stiffness and longitudinal flexibility were compared.
resultsIn CFD simulations, two stents-Pore2-d35 (26.77° weave angle when fully expanded, 35 μm wire thickness) and Pore3-d50 (36.65°, 50 μm respectively)-demonstrated similar flow reduction rates (68.5% spatial-averaged velocity reduction rate, 85.0% area-averaged wall shear stress reduction rate for Pore2-d35, and 68.6%, 85.4%, respectively, for Pore3-d50). However, Pore3-d50 exhibited greater radial stiffness than Pore2-d35 (40.0 vs 21.0 mN/m at a 3.5 mm outer diameter) and less longitudinal flexibility (0.903 vs 0.104 N·mm bending moments at 90°). These measurements indicate that changing the wire thickness and weave angle allows adjustment of the mechanical properties while maintaining the same degree of flow reduction effects.
conclusionsThe combination of CFD and structural analysis can provide promising solutions for an optimized stent. Stents exhibiting different mechanical properties but the same flow reduction effects could be designed by varying both the weave angle and wire thickness.
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