Evidence map›Paper›PMID 27646001›Full record

ArticleThe Journal of biological chemistry2016

MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hi but Not by Ly6ChiTLR2hi Monocytes during Trypanosoma cruzi Infection.

Humberto Doriguêtto Gravina, Alfredo Miranda Goes, Silvane Maria Fonseca Murta, Catherine Ropert

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Humberto Doriguêtto GravinaFrom the Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, 31270-910 Belo Horizonte, Minas Gerais, Brazil and.
Alfredo Miranda GoesFrom the Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, 31270-910 Belo Horizonte, Minas Gerais, Brazil and.
Silvane Maria Fonseca MurtaCentro de Pesquisas René Rachou, Fundação Oswaldo Cruz, 30190-002 Belo Horizonte, Minas Gerais, Brazil.
Catherine RopertFrom the Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, 31270-910 Belo Horizonte, Minas Gerais, Brazil and ropertcatherine@gmail.com.
Universidade Federal de Minas Gerais · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study continues to explore the plasticity of Toll-like receptor 2 (TLR2) previously described in immune response during Trypanosoma cruzi infection. Here, we have shown that Ly6C

Indexed as

AnimalsAntigens, LyChagas DiseaseCytokinesImmunity, InnateMaleMembrane GlycoproteinsMice, Inbred C57BLMonocytesReceptors, Interleukin-1SpleenToll-Like Receptor 2Toll-Like Receptor 9Trypanosoma cruziAntigens, LyCytokinesLy-6C antigen, mouseMembrane GlycoproteinsReceptors, Interleukin-1TIRAP protein, mouseTlr2 protein, mouseTlr9 protein, mouseToll-Like Receptor 2Toll-Like Receptor 9cytokineflow cytometryinfectioninflammationinnate immunityMAL/TIRAPmonocyteToll-like receptor (TLR)

Identifiers

PMID27646001
PMCPMC5095435
OpenAlexW2523144837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.