SynthesisBMC public health2016
Facilitators of HCV treatment adherence among people who inject drugs: a systematic qualitative review and implications for scale up of direct acting antivirals.
Synthesis in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Barriers and facilitators to hepatitis C screening and treatment for people with lived experience of homelessness: A mixed-methods systematic review.Health expectations : an international journal of public participation in health care and health policy · 2022Pooled it
- Distrust in the Health Care System and Adherence to Direct-Acting Antiviral Therapy among People with HepatitisViruses · 2024Trial
- Shame and stigma in association with the HCV cascade to cure among people who inject drugs.Drug and alcohol dependence · 2023Trial
- Progressing towards global hepatitis C elimination: a systematic review and meta-analysis of care cascades in key populations.The Lancet regional health. Western Pacific · 2026Article
- Hepatitis C Care in the Greater New Orleans Area: Patient Perspectives on the Barriers and Facilitators to Care.Journal of health care for the poor and underserved · 2025Article
- Modeling the effects of treatment adherence challenges on the transmission dynamics of hepatitis C virus.PloS one · 2025Article
- Barriers to and impacts of hepatitis C treatment among people who inject drugs in Kenya: A qualitative study.PLOS global public health · 2025Article
- Shorter Duration Hepatitis C Virus Treatment is Associated with Better Persistence to Prescription Refills in People Who Inject Drugs: A Real-World Study.Advances in therapy · 2023Article
- Real-World Effectiveness of 8-Week Glecaprevir/Pibrentasvir in Treatment-Naïve, Compensated Cirrhotic HCV Patients.Infectious diseases and therapy · 2023Article
- Modeling hepatitis C micro-elimination among people who inject drugs with direct-acting antivirals in metropolitan Chicago.PloS one · 2022Article
- Patient Centeredness in Hepatitis C Direct-Acting Antiviral Treatment Delivery to People Who Inject Drugs: A Scoping Review.The patient · 2021Article
- High HCV cure rates among people who inject drugs and have suboptimal adherence: A patient-centered approach to HCV models of care.The International journal on drug policy · 2021Article
- Experiences and Perspectives From Women Taking Investigational Therapy for Hepatitis C Virus During Pregnancy.Substance abuse : research and treatment · 2021Article
- Initial success from a public health approach to hepatitis C testing, treatment and cure in seven countries: the road to elimination.BMJ global health · 2020Review
- Redemption from plight: a qualitative study on reasons behind treatment decisions among Iranian male opioid users.Substance abuse treatment, prevention, and policy · 2020Article
- Provider Perceptions of Hepatitis C Treatment Adherence and Initiation.Digestive diseases and sciences · 2020Article
- From peer-based to peer-led: redefining the role of peers across the hepatitis C care pathway: HepCare Europe.The Journal of antimicrobial chemotherapy · 2019Observational
- Determinants of Hepatitis C Treatment Adherence and Treatment Completion Among Veterans in the Direct Acting Antiviral Era.Digestive diseases and sciences · 2019Article
- Article
- Competing priorities and second chances - A qualitative exploration of prisoners' journeys through the Hepatitis C continuum of care.PloS one · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile the public health benefits of new HCV treatments depend on treatment adherence, particularly among people who inject drugs (PWID), several social and medical factors can jeopardize treatment adherence. The aim of this study is to examine the qualitative literature on facilitators to HCV treatment adherence among PWID.
methodsWe searched six databases to identify qualitative research studies on HCV treatment adherence facilitators among PWID. Two reviewers independently extracted and analyzed data using PRISMA guidelines and the CASP tool to evaluate study quality.
resultsFrom ten studies representing data from 525 participants, three major themes emerged across studies: logistical facilitators within health systems enhanced HCV treatment adherence, positive social interactions between PWID and staff provided positive feedback during treatment, and HCV treatment may complicate the addiction recovery process.
conclusionsAlthough PWID face several barriers to adherence, we identified treatment adherence facilitators that could be incorporated into clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.