Evidence map›Paper›PMID 27645518›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2017

Factors That Predict High Health Care Utilization and Costs for Patients With Inflammatory Bowel Diseases.

Julajak Limsrivilai, Ryan W Stidham, Shail M Govani, Akbar K Waljee, Wen Huang, Peter D R Higgins

Registry-linked trialAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03667586 (The Impact of Group Cognitive Behavioral Psychotherapy on Disease Severity and Psychosocial Functioning of Inflammatory Bowel Disease Patients), which is not on this map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03667586 nacompletednot on this mapstarted 2019, after this paper: background citation

The Impact of Group Cognitive Behavioral Psychotherapy on Disease Severity and Psychosocial Functioning of Inflammatory Bowel Disease Patients

TypeinterventionalSponsorUniversity Hospital of PatrasRan2019 to 2022Enrolled79ConditionsInflammatory Bowel DiseasesArmsGroup cognitive behavioral therapy
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A Care Coordination Intervention Improves Symptoms But Not Charges in High-Risk Patients With Inflammatory Bowel Disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
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  7. Observational
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  10. Guardians at the Gate: Immune System in Gastrointestinal Diseases.International journal of molecular sciences · 2024
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Julajak LimsrivilaiDivision of Gastroenterology, University of Michigan, Ann Arbor, Michigan; Division of Gastroenterology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Ryan W StidhamDivision of Gastroenterology, University of Michigan, Ann Arbor, Michigan.
Shail M GovaniDivision of Gastroenterology, University of Michigan, Ann Arbor, Michigan; VA Center for Clinical Management Research, VA Ann Arbor Health Care System, Ann Arbor, Michigan.
Akbar K WaljeeDivision of Gastroenterology, University of Michigan, Ann Arbor, Michigan; VA Center for Clinical Management Research, VA Ann Arbor Health Care System, Ann Arbor, Michigan.
Wen HuangMedical Center Information Technology, University of Michigan, Ann Arbor, Michigan.
Peter D R HigginsDivision of Gastroenterology, University of Michigan, Ann Arbor, Michigan. Electronic address: phiggins@med.umich.edu.

Funding

Application of Machine Learning Algorithms to Thiopurine Monitoring in IBDR01GM097117 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HIGGINS, PETER D.R. · 2012 to 2016
$1.9M
Improving Prediction of Medical Responsiveness and Clinical Outcomes in Crohn's DiseaseK23DK101687 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STIDHAM, RYAN WILLIAM · 2015 to 2019
$945k
NIDDK NIH HHS K23 DK101687NIGMS NIH HHS R01 GM097117
6 · The paper itself

Abstract

BACKGROUND &

aimsA subset of patients with inflammatory bowel diseases (IBD) have continuously active inflammation, leading to a high number of complications and high direct health care costs (diagnostic tests, medications, and surgeries) and indirect costs (reduced employment and productivity and fewer opportunities for activities). Identifying these high-risk patients and providing effective interventions could produce better outcomes and reduce costs. We used prior year data to create IBD risk models to predict IBD-related hospitalizations, emergency department visits, and high treatment charges (>$30,000/year) in the subsequent year.

methodsWe performed a retrospective study of medical records from all patients with IBD treated at the University of Michigan Hospital from fiscal years 2013-2015. We selected clinical variables from the prior year and tested their abilities to predict 3 adverse outcomes (IBD-related hospitalizations, emergency department visits, and treatment charges >$30,000/year) in the subsequent year. Individual patients were only included once in the data set. We created a multivariate model that was based on a 70% randomly selected cohort (1005 patients) and validated the model on the other 30% (425 patients). Logistic regression was used for bivariate and multivariate analyses.

resultsFactors that predicted high-cost outcomes included the presence of psychiatric illness, use of corticosteroids, use of narcotics, low levels of hemoglobin, and high numbers of IBD-related hospitalizations. In the validation cohort, the model predicted IBD-related hospitalizations, emergency department visits, and high charges in the following year with receiver operating characteristic curve values of 0.751, 0.738, and 0.744, respectively.

conclusionsWe identified 5 factors that can effectively identify patients with IBD at high risk for hospitalization, emergency department visits, and high treatment charges in the next year. These patients should be closely monitored and aggressively managed.

Indexed as

Health Care CostsPatient Acceptance of Health CareAdultAgedEmergency Medical ServicesFemaleHospitalizationHospitals, UniversityHumansInflammatory Bowel DiseasesMaleMichiganMiddle AgedRetrospective StudiesAUROC AnalysisCrohn’s DiseaseManagementUlcerative Colitis

Identifiers

PMID27645518
PMCPMC5503504

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.