Evidence map›Paper›PMID 27645315›Full record

ArticleEuropean journal of immunology2016

Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at-risk phase of autoantibody positive rheumatoid arthritis.

Tamara H Ramwadhdoebe, Janine Hähnlein, Karen I Maijer, Leonard J van Boven, Danielle M Gerlag, Paul P Tak, Lisa G M van Baarsen

Abstract read
In one paragraph

Article in European journal of immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  9. Article
  10. MRI Findings in Axial Psoriatic Spondylarthritis.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamara H RamwadhdoebeAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Janine HähnleinAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Karen I MaijerAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Leonard J van BovenDepartment of Radiology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Danielle M GerlagAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Paul P TakAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
Lisa G M van BaarsenAmsterdam Rheumatology and Immunology Center (ARC), Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The balance between proinflammatory and regulatory CD4

Indexed as

AdultArthritis, RheumatoidAsymptomatic DiseasesAutoantibodiesBiopsyCells, CulturedDisease ProgressionFemaleFollow-Up StudiesHumansImmunophenotypingInterferon-gammaInterleukin-17Lymph NodesLymphocyte ActivationMaleAutoantibodiesInterferon-gammaInterleukin-17AutoimmunityCytokinesLymph nodeRheumatoid arthritisT cellsTh1Th17

Identifiers

PMID27645315
PMCPMC5157721

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.