Evidence map›Paper›PMID 27645110›Full record

ArticleBiochemical pharmacology2016

Identification of novel transplantable GPCR recycling motif for drug discovery.

Mohammed M Nooh, Salvatore Mancarella, Suleiman W Bahouth

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemical pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. The emerging role of sorting nexins in cardiovascular diseases.Clinical science (London, England : 1979) · 2019
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mohammed M NoohDepartment of Pharmacology, The University of Tennessee Health Sciences Center, 71 S. Manassas, Memphis, TN 38103, USA; Department of Biochemistry, Faculty of Pharmacy Cairo University, Kasr El-Aini St., Cairo 11562, Egypt.
Salvatore MancarellaDepartment of Physiology, The University of Tennessee Health Sciences Center, 71 S. Manassas, Memphis, TN 38103, USA.
Suleiman W BahouthDepartment of Pharmacology, The University of Tennessee Health Sciences Center, 71 S. Manassas, Memphis, TN 38103, USA. Electronic address: sbahouth@uthsc.edu.
University of Tennessee Health Science Center · USCairo University · EG

Funding

PKA targeting: A novel mechanism for GPCR resensitizationR01HL085848 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BAHOUTH, SULEIMAN WAKIM · 2009 to 2012
$1.5M
NHLBI NIH HHS R01 HL085848
6 · The paper itself

Abstract

β

Indexed as

Models, MolecularAdrenergic beta-1 Receptor AgonistsBacterial ProteinsDrug DiscoveryEndocytosisEndosomesHEK293 CellsHigh-Throughput Screening AssaysHumansImmunoprecipitationLuminescent ProteinsMicroscopy, ConfocalMicroscopy, FluorescenceOligopeptidesPDZ DomainsPeptide FragmentsADRB1 protein, humanAdrenergic beta-1 Receptor AgonistsBacterial ProteinsFLAG peptideLuminescent ProteinsOligopeptidesPeptide FragmentsPhosphoserineReceptors, Adrenergic, beta-1Receptors, G-Protein-CoupledRecombinant Fusion ProteinsSNX27 protein, humanSorting Nexinsyellow fluorescent protein, BacteriaConfocal microscopyGPCRPDZSNX27Traffickingβ-Adrenergic receptors

Identifiers

PMID27645110
PMCPMC5079812
OpenAlexW2518900853

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.