Evidence map›Paper›PMID 27644420›Full record

ArticleeLife2016

GUY1 confers complete female lethality and is a strong candidate for a male-determining factor in

Frank Criscione, Yumin Qi, Zhijian Tu

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
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  8. Review
  9. Article
  10. Theme and variation in the evolution of insect sex determination.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Natural and Engineered Sex Ratio Distortion in Insects.Frontiers in ecology and evolution · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Identification and Characterization of the Masculinizing Function of theInternational journal of molecular sciences · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Frank CriscioneDepartment of Biochemistry, Virginia Tech, Blacksburg, United States.
Yumin QiDepartment of Biochemistry, Virginia Tech, Blacksburg, United States.
Zhijian TuDepartment of Biochemistry, Virginia Tech, Blacksburg, United States.ORCID 0000-0003-4227-3819
University of Michigan · USInstitute of Entomology · CZ

Funding

Guy1-conferred female lethality: mechanism and application for mosquito controlR01AI121284 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2016 to 2020
$2.0M
Maternal-effect selfish element as gene drive for Anopheles mosquitoesR01AI077680 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2010 to 2014
$1.9M
Function of Guy1, a Y-specific gene of Anopheles stephensiR21AI105575 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2013 to 2014
$428k
Maternal-effect selfish element as gene drive for Anopheles mosquitoesR56AI077680 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2009 to 2009
$385k
NIAID NIH HHS R01 AI077680NIAID NIH HHS R01 AI121284NIAID NIH HHS R21 AI105575NIAID NIH HHS R56 AI077680
6 · The paper itself

Abstract

Despite their importance in sexual differentiation and reproduction, Y chromosome genes are rarely described because they reside in repeat-rich regions that are difficult to study. Here, we show that

Indexed as

Genes, InsectSex DifferentiationY ChromosomeAnimalsAnimals, Genetically ModifiedAnophelesFemaleMaleSurvival AnalysisAnopheleschromosomesembryonic developmentgenesinfectious diseasemalariamicrobiologysex-determinationY chromosome

Identifiers

PMID27644420
PMCPMC5061544
OpenAlexW2522611053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.